Patents Assigned to The Feinstein Institue For Medical Research
  • INTERFERON REGULATORY FACTOR 5 INHIBITORS AND USES THEREOF
    Publication number: 20220220168
    Abstract: Polypeptides comprising a cell penetrating amino acid sequence and an interferon regulatory factor 5 (IRF5) targeting amino acid sequence are disclosed, where the IRF5 targeting amino acid sequence is one or more of RHATRHG (SEQ ID NO:1), KSRDFRL (SEQ ID NO:2) and GPRDMPP (SEQ ID NO:3), as well as methods of using these polypeptides to treat diseases, such as autoimmune and inflammatory diseases.
    Type: Application
    Filed: May 4, 2020
    Publication date: July 14, 2022
    Applicant: THE FEINSTEIN INSTITUES FOR MEDICAL RESEARCH
    Inventors: Betsy J. Barnes, Shan Sun
  • SAA-DOMAIN-SPECIFIC ANTIBODIES AND PEPTIDE ANTAGONISTS AND USE THEREOF TO TREAT INFLAMMATORY DISEASES
    Publication number: 20170029463
    Abstract: Isolated SAA peptides, fusion proteins and compositions comprising such are provided as are domain-specific SAA antibodies. Methods of treating sepsis and endotoxemia are also provided.
    Type: Application
    Filed: September 8, 2016
    Publication date: February 2, 2017
    Applicant: The Feinstein Institue For Medical Research
    Inventors: Haichao Wang, Andrew E. Sama, Wei Li, Kevin J. Tracey