Abstract: A temperature-sensitive hydrogel material combination, a preparation method thereof, and use thereof are provided. The temperature-sensitive gel material combination provided by the present invention includes an SDF-1-loaded chitosan-hyaluronic acid solution and an Apt19S-loaded chitosan-hyaluronic acid solution. The present invention aims to develop a temperature-sensitive injectable double-layer hydrogel loaded with biological factors capable of promoting cell migration, which is used for promoting the regeneration of periodontal tissues.
Type:
Application
Filed:
December 7, 2022
Publication date:
June 29, 2023
Applicant:
THE FIRSTAFFILIATED HOSPITAL OF JINAN UNIVERSITY(GUANGZHOU OVERSEAS CHINESE HOSPITAL)
Inventors:
Xiangning LIU, Mingxiang CAI, Zinan XU, Yan LIANG