Abstract: The invention relates to a system (10) adapted to measure multiple biophysical characteristics of cells, the system (10) comprising: a microfluidic chip (12) provided with a microfluidic channel (14) which allows cells to flow through, the microfluidic channel (14) having an inlet (14a), an outlet (14b), and a lateral opening (14c) situated between the inlet (14a) and the outlet (14b); and a capacitive sensor (30) integrated in the microfluidic chip, adapted to obtain biophysical characteristics of a single cell in the microfluidic channel (14) by directly manipulating the single cell by sensor elements (31, 32) through the lateral opening (14c) of the microfluidic channel (14), the sensor (30) comprising a stationary part and an electrostatically driven movable part which is movable relative to the stationary part, the stationary part being fixed to the microfluidic chip (12), the movable part being arranged in the lateral opening (14c) of the microfluidic channel (14), wherein a portion of the sensor elemen

Abstract: A method of manufacturing a composite member including an aluminum member and a resin member bonded to each other, the method including: performing blasting on a surface of the aluminum member; modifying the surface of the aluminum member into aluminum hydroxide, the modifying including causing the surface of the aluminum member having undergone blasting to react with water by using at least one of heat and plasma; and directly bonding the resin member to the surface of the aluminum member modified to the aluminum hydroxide.

Abstract: A microchamber array device having built-in reaction microchambers, in which the dilution ratio can be greatly increased at the same time as dramatically raising cell recovery efficiency, and an inspection object analysis method using said device are provided. This microchamber array device is provided with: a microchamber array 1 for cell capture by electrophoresis comprising an arrangement of a substrate 2, electrodes 3 and photoresists 4; and a reaction microchamber array 6 which is separated from the capture microchamber array 1, and which is formed from reaction microchamber 8 comprising micro channels 7 arranged so as to be opposite of the aforementioned microchamber array 1.

Abstract: An object is to provide a component for molecular Computing and a method of molecular Computing. A component for molecular Computing, the component comprising: a microsphere including pores, at least some of which are open on a surface of the microsphere, and a plurality of modules grafted on the microsphere wherein each of the modules is a continuous séquence of nucleic acid base.

Abstract: An object to provide an electric device easy to manufacture, extensible and of high quality. The electric device comprises a plurality of module boards 51, the module boards 51 piled up on one another, each of the module boards 51 provided with an electrode 53 on its surface, the electrodes 53 on the piled-up module boards 51 generally positioned along a vertical straight line; and a connector 11 connecting the module boards 51, the connector 11 including a body portion 21, the body portion 21 electrically connecting the electrodes 53 positioned along the vertical straight line, and a holder 12 holding the body portion 21, the holder 12 including a board engagement portion and a holder connecting portion, the board engagement portion engaging with the module board 51 so that the connector 11 is mounted on the module board 51, and the holder connecting portion engaging with another holder connecting portion so that the connector 11 is coupled to another vertically adjacent connector 11.

Abstract: An object to provide an electric device easy to manufacture, extensible and of high quality. The electric device comprises a plurality of module boards 51, the module boards 51 piled up on one another, each of the module boards 51 provided with an electrode 53 on its surface, the electrodes 53 on the piled-up module boards 51 generally positioned along a vertical straight line; and a connector 11 connecting the module boards 51, the connector 11 including a body portion 21, the body portion 21 electrically connecting the electrodes 53 positioned along the vertical straight line, and a holder 12 holding the body portion 21, the holder 12 including a board engagement portion and a holder connecting portion, the board engagement portion engaging with the module board 51 so that the connector 11 is mounted on the module board 51, and the holder connecting portion engaging with another holder connecting portion so that the connector 11 is coupled to another vertically adjacent connector 11.

Abstract: An object is to provide a method of eliminating background amplification in detection of rare nucleic acids based on isothermal amplification. The method comprising steps of: preparing a mixture including solution and enzymes, and adding a first and a second template into the mixture, wherein the first template is an amplification template, and the second template is a leak absorption template. Methods to use this approach for multiplexed, ultrasensitive and ultra-specific detection of nucleic acids are presented.

Abstract: Provided is a method for producing a composite member formed by bonding a base material and a resin member. The method includes: a surface treatment step of forming micro-order or nano-order asperities on a surface of a base material; and a bonding step of directly bonding, by injection molding, a resin member to the surface of the base material that has the asperities formed in the surface treatment step. In addition, the composite member includes: a base material having micro-order or nano-order asperities on a surface thereof; and a resin member that is in direct contact with the surface of the base material.

Abstract: An object is to provide a neuron cultivation device which promptly develops bundles of axons extending from neurons in vitro. A device for cultivating neuron with axon, the device comprising a cultivation plate and a plurality of modules arranged in the cultivation plate. Each of the modules includes at least one of first chambers receivable of cell bodies of neurons at least one of second chambers, and at least one of channels receivable of a bundle of axon extended from the cell bodies. The channels connect the first chambers and the second chambers. Bottom ends of the first chambers, the second chambers and the channels are closed and top ends of the first chambers and the second chambers are open.

Abstract: An object is to make a bridge of DNA expanding between a pair of electrodes, and to characterize the bridge of DNA, to thereby detect DNA easily and surely without employing any marker or labeling substances, such as fluorescent reagents. A method of detecting DNA using a detection device with at least a couple of electrodes, the method comprising immobilizing a primer on the electrodes; making a bridge of the DNA expanded between the electrodes, by immersing the electrodes in a solution including circular templates of single stranded DNA, annealing the circular templates, and generating single stranded DNA product utilizing RCA (Rolling Circle Amplification), with impressing a designated voltage between the electrodes; and characterizing the bridge of DNA which includes multiple single stranded DNA molecules between the electrodes.

Abstract: A method of manufacturing a composite member including an aluminum member and a resin member bonded to each other, the method including: performing blasting on a surface of the aluminum member; modifying the surface of the aluminum member into aluminum hydroxide, the modifying including causing the surface of the aluminum member having undergone blasting to react with water by using at least one of heat and plasma; and directly bonding the resin member to the surface of the aluminum member modified to the aluminum hydroxide.

Abstract: A microchamber array device having built-in reaction microchambers, in which the dilution ratio can be greatly increased at the same time as dramatically raising cell recovery efficiency, and an inspection object analysis method using said device are provided. This microchamber array device is provided with: a microchamber array 1 for cell capture by electrophoresis comprising an arrangement of a substrate 2, electrodes 3 and photoresists 4 and a reaction microchamber array 6 which is separated from the capture microchamber array 1, and which is formed from reaction microchamber 8 comprising micro channels 7 arranged so as to be opposite of the aforementioned microchamber array 1.

Abstract: An object is to provide a neuron cultivation device which promptly develops bundles of axons extending from neurons in vitro. A device for cultivating neuron with axon, the device comprising a cultivation plate and a plurality of modules arranged in the cultivation plate. Each of the modules includes at least one of first chambers receivable of cell bodies of neurons at least one of second chambers, and at least one of channels receivable of a bundle of axon extended from the cell bodies. The channels connect the first chambers and the second chambers. Bottom ends of the first chambers, the second chambers and the channels are dosed and top ends of the first chambers and the second chambers are open.

Abstract: Provided is a method for producing a composite member formed by bonding a base material and a resin member. The method includes: a surface treatment step of forming micro-order or nano-order asperities on a surface of a base material; and a bonding step of directly bonding, by injection molding, a resin member to the surface of the base material that has the asperities formed in the surface treatment step. In addition, the composite member includes: a base material having micro-order or nano-order asperities on a surface thereof; and a resin member that is in direct contact with the surface of the base material.

Abstract: A viscosity/elasticity measurement device includes a container for containing a measurement target material for detection of viscosity/elasticity is contained, a floating rotor made of material including a conductor, formed in a plate and circular shape when seen in plan view, and configured to be floated on a surface of the measurement target material, a magnet applying a magnetic field to the floating rotor in a direction perpendicular to a surface of the measurement target material, a rotational magnetic field control unit driving the magnet to apply a rotational magnetic field to the floating rotor, inducing an induction current in the conductor, and applying rotational torque to the floating rotor to rotate by Lorentz interaction between the induction current and the magnetic field applied to the floating rotor, and a viscosity detection unit detecting the viscosity/elasticity of the measurement target material based on a rotation state of the floating rotor.

Abstract: An object is to make it possible to determine and output an accurate current position reliably in a short time and at a low cost, even in environments where signals from positioning satellites are complicatedly affected by structures, geographical features, etc. Therefore, the present invention provides a position detection device comprising: a receiving unit receiving signals from a positioning satellite, and calculating a pseudo range to the positioning satellite based on the signals, and a positioning unit calculating an initial position based on the pseudo range calculated by the receiving unit, calculating the pseudo range to the positioning satellite at plural positions around the initial position using a three-dimensional map data and a ray-tracing method, selecting candidate positions from the plural positions based on the pseudo range, and deciding a current position based on the candidate positions within such a short distance from the initial position that predetermined conditions are satisfied.

Abstract: The present invention makes it possible to easily and efficiently observe a specimen contained in a fluid without using a filtration device separate from a scanning probe microscope by attaching a filter holding part holding a filter to a fluid cell of a specimen support. Therefore, a specimen support 10, for holding a specimen subject to observation by the scanning probe microscope, comprises a fluid cell 11, into which fluid including the specimen is introduced, and a filter unit including a filter 15, which allows the fluid passage and at least a part of the specimen is adhered to. The fluid cell 11 includes a fluid entrance, the filter unit includes a fluid exit opening, and the filter unit is attached to one side of the fluid cell 11.

Abstract: An object is to measure a mechanical property of a fluid at a temporal resolution of at least 100 [?s]. Therefore, a method comprising: causing a droplet 21 to fly by ejecting a fluid to be measured from a nozzle 11a as the droplet 21; generating an electric field in a space around a flight path 22 of the droplet 21 by applying a voltage to an electrode arranged in the vicinity of the flight path 22; deforming the droplet 21 in a way of contactless deformation with a dielectric force induced by the electric field; and measuring a mechanical property of the fluid based on temporal variation of deformation state of the droplet 21 after deforming the droplet 21.

Abstract: The present invention relates to a radioactive cesium adsorbent, a method for producing the same, and a method for decontaminating the environment from radioactive cesium with the adsorbent. The radioactive cesium adsorbent of the present invention includes a hydrophilic fiber substrate supporting a Prussian blue analog, in particular, Prussian blue, and the Prussian blue analog is immobilized in the inside of the fibers.

Abstract: An object is to make it possible to determine and output an accurate current position reliably in a short time and at a low cost, even in environments where signals from positioning satellites are complicatedly affected by structures, geographical features, etc. Therefore, the present invention provides a position detection device comprising: a receiving unit receiving signals from a positioning satellite, and calculating a pseudo range to the positioning satellite based on the signals, and a positioning unit calculating an initial position based on the pseudo range calculated by the receiving unit, calculating the pseudo range to the positioning satellite at plural positions around the initial position using a three-dimensional map data and a ray-tracing method, selecting candidate positions from the plural positions based on the pseudo range, and deciding a current position based on the candidate positions within such a short distance from the initial position that predetermined conditions are satisfied.