Abstract: The invention relates to cross-link-resistant injectable hydrogel formulations and methods of partially or practically wholly inhibiting injectable hydrogel formulations from cross-linking, for example, during irradiation, using anti-cross-linking agents, which facilitates injectability of the hydrogel formulation. The invention also relates to methods of making the cross-link-resistant, for example, irradiation cross-link resistant, injectable hydrogel formulations, and methods of administering the same in treating a subject in need.
Type:
Application
Filed:
September 15, 2008
Publication date:
February 26, 2009
Applicant:
The General Hospital Corporation dba Massachusetts Ceneral Hospital
Inventors:
Orhun K. Muratoglu, Ebru Oral, Hatice Bodugoz-Senturk