Patents Assigned to THE GOV'T OF THE U.S. OF AMERICA REPRESENTED BY THE SECRETARY OF THE DEPT H&HS
  • THERAPEUTIC APPLICATIONS OF P53 ISOFORMS IN REGENERATIVE MEDICINE, AGING AND CANCER
    Publication number: 20110243968
    Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.
    Type: Application
    Filed: October 21, 2008
    Publication date: October 6, 2011
    Applicant: THE GOV'T OF THE U.S. OF AMERICA REPRESENTED BY THE SECRETARY OF THE DEPT H&HS
    Inventors: Curtis C. Harris, Kaori Fujita, Izumi Horikawa, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane