Patents Assigned to The Governers of the University of Alberta
  • Boronic acid catalysts and methods of use thereof for activation and transformation of carboxylic acids
    Patent number: 9284270
    Abstract: The present application provides methods and catalysts for activation of carboxylic acids for organic reactions.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: March 15, 2016
    Assignees: The Governers of the University of Alberta, Greencentre Canada
    Inventors: Dennis Hall, Nicolas Gernigon, Raed M. Al-Zoubi, Paul D. Thornton
  • Electrostatically regulated atomic scale electroconductivity device
    Patent number: 8076668
    Abstract: An atomic scale electroconductivity device with electrostatic regulation is provided that includes a perturbing species having a localized electronic charge ol a dangling bond. A sensing species having an electronic conductivity is placed in proximity to the perturbing species at a distance sufficient to induce a change in the electronic conductivity associated with the localized electronic charge. Electronics are provided to measure the conductivity via the sensing species. The dangling bond functions as a single atom gate electrode.
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: December 13, 2011
    Assignees: The Governers of the University of Alberta, National Research Council of Canada
    Inventors: Robert A. Wolkow, Paul G. Piva, Jason L. Pitters, Gino A. Dilabio
  • ?-1,3 fucosyltransferases and expression systems for making and expressing them
    Patent number: 6962806
    Abstract: A bacterial ?1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing ?1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: November 8, 2005
    Assignee: The Governers of the University of Alberta
    Inventors: Diane E. Taylor, Zhongming Ge
  • Nucleic acids encoding alpha-1,3 fucosyltransferases and expression systems for making and expressing them
    Publication number: 20020068347
    Abstract: A bacterial &agr;1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing &agr;1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Application
    Filed: December 7, 2000
    Publication date: June 6, 2002
    Applicant: The Governers of the University of Alberta, a Canada corporation
    Inventors: Diane E. Taylor, Zhongming Ge
  • Treatment of diarrhea caused by enteropathogenic Escherichia coli
    Patent number: 6291435
    Abstract: This invention relates to compositions and methods useful to treat diarrhea, especially diarrhea and related conditions initiated or mediated by enteropathogenic E. coli (EPEC), using oligosaccharide compositions. This invention also relates to compositions and methods to reduce the virulence of an EPEC organism.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: September 18, 2001
    Assignee: The Governs of the University of Alberta
    Inventors: Rosa P. Yanmaele, Glen D. Armstrong