Patents Assigned to The Government of the United States, as represented by the Secretary of the Army
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Patent number: 11963959Abstract: Inhibitors against SARS-COV-1, SARS-CoV-2 (Covid-19), MERS-CoV, and variants within each, including methods of treating a subject suffering from such respiratory disease.Type: GrantFiled: August 12, 2022Date of Patent: April 23, 2024Assignees: Southwest Research Institute, The Government of the United States, as represented by The Secretary of the Army, The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Inventors: Jonathan A. Bohmann, Nadean M. Gutierrez, Joseph A. Mcdonough, Robert Francis Campbell, Michael Gordon Joyce, Rekha Panchal, Rajeshwer Sankhala, Allen Duplantier
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Patent number: 11961009Abstract: Various embodiments that pertain to artificial intelligence algorithms. A repository can retain a reusable common set of artificial intelligence algorithms. Different users can access this common set of artificial intelligence algorithms and employ individual artificial intelligence algorithms in programs as appropriately as they are developing different applications and/or products. Employment of these individual artificial intelligence algorithms can include, for example, tailoring parameters based on the desires of the individual user's desires using the same common set of algorithms or individually or as a group as appropriate.Type: GrantFiled: November 2, 2020Date of Patent: April 16, 2024Assignee: The Government of the United States, as represented by the Secretary of the ArmyInventor: Radhika Roy
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Patent number: 11953295Abstract: An explosive reactive armor (ERA) enclosure for an ERA tile includes a bottom and a plurality of sidewalls extending from the bottom, where the plurality of sidewalls are continuous with each other and with the bottom so as to define an internal volume. The plurality of sidewalls are formed from a fiber-reinforced composite material having a plurality of plies of fiber sheet material. Additionally, a sidewall seam defined by abutting edges of the first ply is offset from a sidewall seam defined by abutting edges of the second ply. Methods of manufacturing ERA enclosures, including applying wrap layers and forming attachment structures for securing the fiber-reinforced composite ERA enclosure to an armor element, are also described. The composite enclosure is inexpensive and lightweight and improves the dynamic capabilities of armored vehicles using such ERA tiles.Type: GrantFiled: December 19, 2022Date of Patent: April 9, 2024Assignee: Government of the United States, as represented by the Secretary of the ArmyInventors: Shawn C. Klann, Frederick C. Rickert, II, David B. Witherspoon, William T. Hoffman
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Patent number: 11952275Abstract: A method for controlling a fuel reformation reaction in a fuel reformation reactor is provided. Furthermore, a non-transitory computer-readable storage medium is provided, which is configured to store a program for controlling a fuel reformation reaction in a fuel reformation reactor. In addition, a fuel reformation system for controlling a fuel reformation reaction is provided, which includes a fuel reformation reactor and a control unit.Type: GrantFiled: June 12, 2018Date of Patent: April 9, 2024Assignee: The Government of the United States, as represented by the Secretary of the ArmyInventors: Richard Scenna, Ashwani Gupta
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Publication number: 20240082233Abstract: Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I): A compound of Formula (I) can be administered prior to potential exposure of a species of Plasmodium, during potential exposure of a species of Plasmodium, and after potential exposure of a species of Plasmodium. The methods of the invention also pertains to kits comprising specific doses of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I), and instructions for administration of dosing quantity and frequency. The methods of the invention also pertain to determining doses of Formula (I) that meet the general regulatory requirement for a drug to be efficacious in the prevention of malaria in malaria-naïve subjects.Type: ApplicationFiled: August 30, 2023Publication date: March 14, 2024Applicants: 60 DEGREES PHARMACEUTICALS LLC, THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMYInventors: Geoffrey S. DOW, Bryan L. SMITH, John P. JONES, Moshe SHMUKLARSKY, Budda BALASUBRAHMANYAM
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Patent number: 11912946Abstract: Various embodiments that pertain to fuel processing are described. A fuel processor can produce an endothermic reaction that cools a substance and produces a processed fuel from a raw fuel. A generator can employ the processed fuel to produce an electricity. The generator can supply the electricity to a load that uses the electricity to function. The load can become hot due to its functioning and can benefit from being cooled. The substance cooled by the fuel processor can cool load and in the process the substance can rise in temperature. This warmer substance can be transferred to the fuel processor to be cooled again and this cycle can continue. Further, the fuel processor can use the warmer substance to achieve the endothermic reaction.Type: GrantFiled: March 29, 2021Date of Patent: February 27, 2024Assignee: The Government of the United States, as represented by the Secretary of the ArmyInventors: Michael Seibert, Richard Scenna, Terry DuBois
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Patent number: 11916315Abstract: Various embodiments that relate to a circular disk configured to radiate a signal. The radiating disk can include edge openings. Within these edge openings power supplies can rest. When the power supplies function, they can cause the circular disk to radiate with either a dipole pattern or a cardioid pattern. A controller can manage how these power supplies function depending on if the dipole pattern or the cardioid pattern is desired.Type: GrantFiled: November 10, 2021Date of Patent: February 27, 2024Assignee: The Government of the United States, as represented by the Secretary of the ArmyInventors: Brandon Underwood, Glenn Minko
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Patent number: 11911208Abstract: Improved systems and methods for diagnosing an injury of a patient. The system and methods provide for more accurate scans of the injury thereby enabling a combat medic, a medical technician, or even untrained individuals to quickly diagnose the injury. By providing more accurate information, the systems and methods provide the technician with additional information regarding treatment options, such as whether to transport the patient or treat the patient in place, potential for aspiration, and other information about dangerous fluid build-up such as size, depth, and types of surrounding tissues, thereby increasing survivability of the patient. The systems and methods can also provide a diagnosis of the injury as well as suggestions on actions to take to treat the patient.Type: GrantFiled: August 21, 2019Date of Patent: February 27, 2024Assignee: The Government of the United States, as Represented by the Secretary of the ArmyInventors: Jose Salinas, Ronald D. Grisell, Sena R. Veazey, Saul J. Vega
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Patent number: 11884718Abstract: The invention described herein provides antibodies to Zika virus. The novel polypeptides are useful alone or as portions of larger molecules, such as antibodies or antibody fragments, that can be used to treat or prevent infection of Zika virus.Type: GrantFiled: April 24, 2019Date of Patent: January 30, 2024Assignees: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Beth Israeli Deaconess Medical Center, Inc., The Government Of The United States As Represented By The Secretary Of The ArmyInventors: Shelly Krebs, Gina Donofrio, Vincent Dussupt, Kayvon Modjarrad, Dan Barouch, Richard G. Jarman, III, Nelson L. Michael, Gordon Joyce, Rajeshwer Singh Sankhala, Kathryn Elaine Stephenson
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Patent number: 11883194Abstract: A system, method and apparatus is disclosed, comprising a biomathetical model for optimizing cognitive performance in the face of sleep deprivation that integrates novel and nonobvious biomathematical models for quantifying performance impairment for both chronic sleep restriction and total sleep deprivation; the dose-dependent effects of caffeine on human vigilance; and the pheonotypical response of a particular user to caffeine dosing, chronic sleep restriction and total sleep deprivation in user-friendly software application which itself may be part of a networked system.Type: GrantFiled: January 11, 2022Date of Patent: January 30, 2024Assignee: The Government of the United States, as represented by the Secretary of the ArmyInventors: Jaques Reifman, Jianbo Liu, Nancy Wesensten, Thomas Balkin, Sridhar Ramakrishnan, Maxim Y. Khitrov
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Publication number: 20240017214Abstract: A portable filtration system is described. The system may comprise: a mixing portion, comprising: a pump adaptor and a contaminant regulator. The pump adaptor may comprise: an upper plate, a lower plate, and a screen. The screen may axially extend between the upper and lower plates, wherein the upper plate, the lower plate, and the screen define a channel of a mixing chamber. The contaminant regulator may comprise a through-passage coupled to the upper plate, wherein the through-passage is in fluid communication with the mixing chamber.Type: ApplicationFiled: September 29, 2023Publication date: January 18, 2024Applicant: Government of the United States, as represented by the Secretary of the ArmyInventors: Michael Jeffrey Anderson, Jeremy Stephen Walker, James Saye Dusenbury, IV
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Publication number: 20240017775Abstract: A band track including a band having an inner surface, an outer surface, a first side face, and a second side face; a plurality of teeth extending from the inner surface and spaced apart circumferentially around the inner surface; a plurality of lugs extending from the outer surface and each spaced a distance apart circumferentially around the outer surface; a plurality of living hinges defined within the band circumferentially between each of the plurality of teeth; and at least one fiber-reinforcement disposed circumferentially within a neutral plane of the plurality of living hinges and a method of making the same.Type: ApplicationFiled: September 28, 2023Publication date: January 18, 2024Applicant: Government of the United States, as represented by the Secretary of the ArmyInventors: Robert James Hart, Andrew Quintin Smail
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Patent number: 11865111Abstract: Antiviral drugs targeting the N-terminal domain (NTD) of the spike receptor binding domain (RBD) and methods of treating a subject suffering from coronavirus.Type: GrantFiled: August 11, 2022Date of Patent: January 9, 2024Assignees: Southwest Research Institute, The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Government of the United States, as Represented by the Secretary of the ArmyInventors: Jonathan A. Bohmann, Nadean M. Gutierrez, Joseph A. McDonough, Robert Francis Campbell, Michael Gordon Joyce, Rekha Panchal, Rajeshwer Sankhala, Allen Duplantier
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Patent number: 11866168Abstract: An enclosure for a UAS includes a housing having a base and a plurality of sidewalls coupled to the base, a motive apparatus coupled to the housing, a platform coupled to the motive apparatus, and a plurality of lids pivotably coupled to the sidewalls and the platform. The platform and the plurality of lids move collectively under control of the motive apparatus (e.g., a linear actuator). Driving the motive apparatus in a first direction causes the platform to raise from a stowed position toward a deployed position and causes each of the plurality of lids to pivot from a closed position toward an open position. Conversely, driving the motive apparatus in a second direction opposite the first direction causes the platform to lower from the deployed position toward the stowed position and causes each of the plurality of lids to pivot from the open position toward the closed position.Type: GrantFiled: September 27, 2021Date of Patent: January 9, 2024Assignee: Government of the United States, as represented by the Secretary of the ArmyInventors: Neil E. Cooper, Eric S. Paternoster, Jason A. Schrader, Gary L. Bronstetter
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Patent number: 11859214Abstract: An in vitro model of an in vivo gastrointestinal tract including an in vitro model of an in vivo small intestine including a plurality of fermentation vessels and an in vitro model of an in vivo large intestine including a plurality of fermentation vessels is provided. A method of simulating a biotransformation of food product through the human digestive tract using an in vitro model of an in vivo gastrointestinal tract is provided.Type: GrantFiled: August 15, 2019Date of Patent: January 2, 2024Assignee: The Government of the United States, as represented by the Secretary of the ArmyInventors: Laurel A Doherty, Jason W Soares, Steven Arcidiacono, Sarah Pearce
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Patent number: 11849781Abstract: Apparel that is adjustable. For example, in one embodiment, the apparel is provided that includes a torso. The torso includes a front, a back, a first side connecting the front to the back, a second side connecting the front to the back, a bottom, and a top. A plurality of shell fabric portions is on the torso. Each portion in the plurality of portions of shell fabric is adapted to receive an elastomeric member. Bunched fabric is on the first side and second side of the torso. Pleats are on the front of the torso. A centrally located flap is on the torso and has a longitudinal axis that is substantially vertical. Sleeves are connected to the torso. A first zipper track is located on the bottom of the torso. Pants may include a second zipper track adapted to mate with the first zipper track and secure the pants to the torso.Type: GrantFiled: April 25, 2022Date of Patent: December 26, 2023Assignee: Government of the United States as Represented by the Secretary of the ArmyInventor: Haile A. Merrill
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Patent number: 11844714Abstract: An exoskeletal orthosis includes a proximal cuff including a hinge along an upper edge of the cuff; an ankle section/footplate; and at least one posterior strut connecting the proximal cuff to the ankle section and foot plate.Type: GrantFiled: August 31, 2021Date of Patent: December 19, 2023Assignee: The Government of the United States As Represented By the Secretary of the ArmyInventor: Ryan V. Blanck
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Publication number: 20230390389Abstract: A nucleic acid vaccine composition comprising one or more of a plasmid-based nucleic acid vaccine and immunotherapy, as well as a lipid formulation, is provided. In addition, the present invention provides a method of enhancing the potency of plasmid-based DNA vaccines and immunotherapies, by formulating a vaccine and/or immunotherapy in a lipid formulation, which is stable when refrigerated or stored frozen, is then delivered to a vaccinee by either needle/syringe, jet injection, or microneedles. The lipid formulation of the present invention comprises one or more lipid excipients selected from 1,2-Distearoyl-sn-glycero-3-phosphocholine, Cholest-5-en-3?-ol, 1,2-Dimyristoyl-rac-glycero-3-methylpolyoxyethlene, and or more symmetric ionizable cationic lipids. The present invention increases vaccine potency dramatically.Type: ApplicationFiled: August 18, 2023Publication date: December 7, 2023Applicants: The Government of the United States, as Represented by the Secretary of the Army, Arcturus Therapeutics, Inc.Inventors: Jay W. HOOPER, Eric M. MUCKER, Padmanabh CHIVUKULA
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Publication number: 20230379226Abstract: A communication system provides multimedia communications within and between armored ground combat vehicles (GCVs). The system includes client computers within the armored GCVs providing distributed and interconnected multimedia communications among the client computers. The multimedia communication may include a one-to-one communication, a text communication to a group, an audio communication to a group, or a video communication to a group. Logic providing the distributed and interconnected multimedia communications is not located at a single client computer. The client computers display graphical user interfaces (GUIs) enabling soldiers to select parameters of the communication system with some GUIs providing presence discovery among the armored GCVs. One of the plurality of client computers acts as an origination station and other client computers may be configured as receiving communication station(s).Type: ApplicationFiled: February 6, 2023Publication date: November 23, 2023Applicant: GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMYInventors: Olatunde O. Bamgboye, Eric Bennett
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Patent number: 11822105Abstract: The disclosed subject matter relates to relate to fibers, textiles, fabrics, clothing and methods that are retroreflective including fibers having a hollow sheath that is filled with retroreflective particles.Type: GrantFiled: December 7, 2021Date of Patent: November 21, 2023Assignee: The Government of the United States, as represented by the Secretary of the ArmyInventors: Michael Ghebrebrhan, Eric Wetzel