Patents Assigned to The Government of the United States of America, as a representative by the Secretary of the Depart
  • Publication number: 20090137005
    Abstract: The present invention provides for nucleic acids improved for the expression of interleukin-12 (IL-12) in mammalian cells. The invention further provides for methods of expressing IL-12 in mammalian cells by transfecting the cell with a nucleic acid sequence encoding an improved IL-12 sequence.
    Type: Application
    Filed: January 12, 2007
    Publication date: May 28, 2009
    Applicant: The Government of the United States of America, as a representative by the Secretary of the Depart
    Inventors: Barbara Felber, George N. Pavlakis, Margherita Rosati