Patents Assigned to The Government of the United States of America, as Represented by the Secretary, Department of Hea
  • AEROSOL GENERATOR
    Publication number: 20110108023
    Abstract: A sonic aerosol generator is provided that provides a constant concentration of particulate aerosol over a long exposure time to an animal. The concentration of aerosols is maintainable for greater than 30 hours at concentrations of 15 mg/m3 or more. The aerosol generator is used to expose subject to high concentrations of aerosols that more accurately represents the levels that may be seen in a workplace environment.
    Type: Application
    Filed: August 30, 2010
    Publication date: May 12, 2011
    Applicant: The Government of the United States of America, as represented by the Secretary, Department of Hea
    Inventors: Walter McKinney, Dave Frazer, Bean Chen
  • JANUS FAMILY KINASES AND IDENTIFICATION OF IMMUNE MODULATORS
    Publication number: 20090137787
    Abstract: An isolated polynucleotide encodes JAK-3 protein. JAK-3 protein is a protein tyrosine kinase having a molecular weight of approximately 125 kDa which has tandem non-identical catalytic domains, lacks SH2 or SH3 domains, and is expressed in NK cells and stimulated or transformed T cells, but not in resting T cells. The protein itself and antibodies to this protein are also presented. Further, methods of identifying therapeutic agents for modulating the immune system make use of the foregoing.
    Type: Application
    Filed: January 15, 2009
    Publication date: May 28, 2009
    Applicant: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEA
    Inventors: John J. O'Shea, Warren J. Leonard, James A. Johnston, Sarah M. Russell, Daniel W. McVicar, Masaru Kawamura
  • Biofunctionalized quantum dots for biological imaging
    Publication number: 20070172427
    Abstract: Novel biofunctionalized quantum dots include a mercaptoalkanoic acid linked to the surface of a nanocrystalline core and a bio-functional group linked to the surface. Biofunctionalized quantum dots are made by a novel synthesis method. Biofunctionalized quantum dots can be used in imaging or therapy applications.
    Type: Application
    Filed: November 5, 2003
    Publication date: July 26, 2007
    Applicant: The Government of the United States of America, as Represented by the Secretary, Department of Hea
    Inventors: Joseph Barchi, Serge Svarovsky