Abstract: Botanical Combination therapies for treating AIDS and immune-deficient patients include therapeutically effective doses of five medicinal plants of Thailand. First combination, ayurvedic composition 1, consists of ground and spray-dried plant extracts Houttuynia cordata, Combretum quadrangulare, Mimusops elengi, Randia siamensis, and Borassus flabellifer in the varied amount. Drug mixture is administered one capsule twice daily. Second combination therapy consists of ayurvedic composition 1 (one capsule twice daily) plus one capsule of ayurvedic composition 2 twice daily. Ayurvedic composition 2 is powder of Houttuynia cordata extract in varied amounts. Ayurvedic composition 3 consists of dried extracts of five plant materials in fixed amounts. Ayurvedic composition 4 is dried extract of Houttuynia cordata 100 mg.