Abstract: The present invention provides a method for preparing a pharmaceutical formulation containing ivermectin and a method and composition that can contain ivermectin plus tetrahydropyrimidines. An examples of a tetrahydropyrimidine includes pyrantel. A pharmaceutical formulation is provided for use in the treatment of helminthiasis of mammals, and particularly tapeworm, hookworm, roundworm and heartworm of domestic animals and farm animals. The present invention also provides a method of treating helminthiasis in mammals, which method comprises administering to the mammal in need thereof an anthelmintically effective amount of a pharmaceutical formulation of the invention.
Abstract: An improved blister package construction is provided. The inventive blister package construction allows for different visual presentations of the packaged products that would otherwise not be achievable with conventional blister packages. The blister package of the invention has one or two thermoplastic blisters designed and positioned on a backing card such that, when the card is folded along a transverse score line, the one or two blisters will lock together and the backing card will be formed into an āLā shaped configuration.
Abstract: The present invention provides a method for preparing a pharmaceutical formulation containing ivermectin and a method and composition that can contain ivermectin plus hexahydropyrazinoisoquinolines, tetrahydropyrimidines and benzimidazoles or febantel. Examples of hexahydropyrazinoisoquinolines, tetrahydropyrimidines and benzimidazoles include praziquantel, pyrantel pamoate and fenbendazole, respectively. A pharmaceutical formulation is provided for use in the treatment of helminthiasis of mammals, and particularly tapeworm, hookworm, roundworm, whipworm and heartworm of domestic animals and farm animals. The present invention also provides a method of treating helminthiasis in mammals, which method comprises administering to the mammal in need thereof an anthelmintically effective amount of a pharmaceutical formulation of the invention.
Type:
Grant
Filed:
March 12, 2004
Date of Patent:
July 8, 2008
Assignees:
Virbac Corporation, The Hartz Mountain Corporation
Inventors:
Ian Cottrell, Arima Das Nandy, Albert Ahn, Richard Fisher
Abstract: The present invention provides a method for preparing a pharmaceutical formulation containing ivermectin and a method and composition that can contain ivermectin plus hexahydropyrazinoisoquinolines and tetrahydropyrimidines. Examples of these include praziquantel and pyrantel. A pharmaceutical formulation is provided for use in the treatment of helminthiasis of mammals, and particularly tapeworm, hookworm, roundworm and heartworm of domestic animals and farm animals. The present invention also provides a method of treating helminthiasis in mammals, which method comprises administering to the mammal in need thereof an anthelmintically effective amount of a pharmaceutical formulation of the invention.
Type:
Grant
Filed:
August 8, 2003
Date of Patent:
July 8, 2008
Assignees:
Virbac Corporation, The Hartz Mountain Corporation
Inventors:
Michael Burke, Vinay Tripathi, Albert Ahn, Ian Cottrell
Abstract: A lint roll apparatus includes an orienting mechanism for orienting the free edge of the outermost sheet of a adhesive roll with a predetermined point on a roll support. Orientation is implemented by cooperating stop members on the roll and the roll support, by a slidable member on the roll support moveable into and out of engagement with a notch in the roll or a roll core, or a trigger activated moveable pin which is engagable with a stop member carried on the roll or roll support. A motor driven spindle rotates a cylinder on which the roll is mounted.
Abstract: A cleaning apparatus includes a handle, a support coupled to the handle and a cleaning element mountable on the support. The support is fixed to the handle or is rotatably coupled to the handle for rotation by a drive motor mounted in the handle. The cleaning element may include bristles extending from a flexible mat fixed about the support or about a core mountable on the support. A cleaning sheet is windable about the support, the core or the cleaning element, including over and through the bristles, for dual cleaning action.
Abstract: A cleaning apparatus includes a substrate with outward projecting bristles extending through a sheet or scrim impaled over the bristles. The substrate may be mounted on a support which may carry a handle. The sheets may be single sheets arranged in a stack over the bristles on one or more surfaces of the substrate or a roll of separable sheets disposed over the bristles.
Abstract: A cleaning apparatus includes a substrate with outward projecting bristles. The substrate may be mounted on a support which may carry a handle or on a media dispensing container. The handle is hollow to carry a dispensable media from a dispenser mounted on the handle or has an open end to receive an aerosol or media dispensing container.
Abstract: An improved cleaning tool is provided with a flexible connection between the head or spindle and the handle. The improved tool broadly includes a spindle or head, a handle and a flexible connection between the head and handle to permit relative pivotal movement therebetween and rubber bumpers to protect against scratching furniture. The flexible connection regulates relative movement between the spindle head in such a way that lateral movement is greater than the up and down movement.