Abstract: The present invention discloses a method for detecting the mechanical response of a mechanical component by an organic mechanoresponsive fluorescent material, comprising the following steps of: selecting an organic mechanoresponsive fluorescent material; preparing an organic mechanoresponsive fluorescent material solution; forming a film on a metal surface; calibrating fluorescence intensity and obtaining the fluorescence intensity and distribution in a crack tip area; observing the fluorescence signal generated at cracks to monitor the occurrence of fatigue cracks, and predict a propagation pathway of fatigue cracks by using the fluorescence intensity distribution in the crack tip area.
Type:
Grant
Filed:
April 26, 2018
Date of Patent:
March 15, 2022
Assignees:
Tianjin University, The Hong Kong University of Science and Technology
Abstract: Methods and devices for a spintronic device of spin-orbit torque magnetic random access memory (SOT-MRAM) are provided. A unit cell of a device can comprise a ferromagnetic (or ferrimagnetic or antiferromagnetic) layer on the heavy metal layer, and a current source configured to transmit either non-collinear current pulses in the heavy-metal layer or two perpendicular currents in the heavy metal layer. The current pulses exhibit a phase difference, and the magnitude of a sum of the respective current pulses is constant (in its simplest form) and the flow direction of the pulses is time-dependent.
Type:
Grant
Filed:
November 28, 2018
Date of Patent:
March 15, 2022
Assignee:
The Hong Kong University of Science and Technology
Abstract: A visual tracker can be configured to obtain profile data associated with a pose of a living entity. In response to detecting a person, a camera can be selected from cameras. Additionally, in response to selecting the camera, the system can receive video data from the camera representative of a stance of the person. Consequently, the stance of the person can be estimated, resulting in an estimated stance.
Type:
Grant
Filed:
October 31, 2017
Date of Patent:
February 15, 2022
Assignee:
The Hong Kong University of Science And Technology
Abstract: Provided herein are recombinant peptides useful for inhibiting the function of autophagy-related 8 (Atg8) proteins. The recombinant peptides can be used in the preparation of imaging agents for monitoring autophagy in a cell or subject and treating autophagy related diseases, such as cancer.
Type:
Grant
Filed:
November 5, 2018
Date of Patent:
January 25, 2022
Assignee:
The Hong Kong University of Science and Technology
Inventors:
Mingjie Zhang, Jianchao Li, Ruichi Zhu, Chao Wang
Abstract: The present disclosure provides an energy conversion system and method for generating electricity directly from heat by phase transformation of ferroelectric materials without any external power sources. The energy conversion system includes an electric circuit comprising a phase-changing capacitor and a charge reservoir. The phase-changing capacitor has a dielectric layer comprising a phase-transforming ferroelectric material. When the phase-changing capacitor is initialized and subjected to thermal cycles through a transformation temperature of the phase-transforming ferroelectric material, the polarization of the dielectric layer undergoes an abrupt change between a ferroelectric phase and a paraelectric phase such that a current flow between the phase-changing capacitor and the charge reservoir via a load thereby converting heat into electrical energy. The present energy conversion method does not require any external bias fields during the energy conversion.
Type:
Grant
Filed:
March 27, 2020
Date of Patent:
January 18, 2022
Assignee:
The Hong Kong University of Science and Technology
Abstract: Provided herein is a sequentially processed fabrication method involving donor-acceptor conjugated polymers with temperature dependent aggregation (TDA) useful for the preparation of organic semiconductors with improved properties.
Type:
Grant
Filed:
April 25, 2018
Date of Patent:
December 21, 2021
Assignee:
The Hong Kong University of Science and Technology
Abstract: A Pd—Ru alloy catalyst for hydrogen production and its preparation methods are provided. The catalyst can include a plurality of particles comprising an alloy of at least palladium (Pd) and ruthenium (Ru). Moreover, the catalyst can further include a support material such as carbon support having external or internal surfaces on which the plurality of particles is dispersed. The alloy catalyst can have a molar ratio of Pd:Ru in a range of about 0.5:1 to about 9:1. For hydrogen evolution reaction (HER), the Pd—Ru alloy catalyst exhibits increased catalytic activities comparing to some well-known catalysts.
Type:
Grant
Filed:
March 22, 2019
Date of Patent:
December 7, 2021
Assignee:
The Hong Kong University of Science and Technology
Abstract: Techniques for fingertip design are disclosed that leverage how most grasp contacts can share a few classes of local geometries. In order to maximize the contact areas for achieving more robust grasps, contact primitives, which represent a set of contacts of similar local geometries, are identified. A uniform cost algorithm, which can be formulated as a decision making process in a tree structure, can be utilized to cluster a set of example grasp contacts into a finite set of one or more contact primitives. Fingertips can be designed by optimization to match the local geometry of each contact primitive, and then fingertips can be 3D printed using soft materials to compensate for optimization residuals. For novel objects, an approach to generate grasp contacts that match the fingertip geometries while together forming stable grasps can be utilized.
Type:
Grant
Filed:
November 15, 2018
Date of Patent:
November 30, 2021
Assignee:
The Hong Kong University of Science And Technology
Abstract: An eyedrop composition, and methods of making and using the same, may include one or more hydrogel forming polymer having an intrinsic viscosity [?] of at least 3 dL/g in the composition, wherein a concentration CT of such hydrogel forming polymer in the composition is at most about 5 mg/mL.
Type:
Application
Filed:
September 18, 2019
Publication date:
November 18, 2021
Applicant:
The Hong Kong University of Science and Technology
Abstract: A leakage location in a viscoelastic pipe is estimated by generating a transient wave at a downstream node of the pipe. Liquid pressures at plural locations along the pipe are measured. Measured signals are transformed to frequency response functions (FRFs). The FRF from a sensor closest to the upstream node is used to estimate a FRF of transient discharge at the upstream node. A frequency-dependent wave speed of the transient wave is computed according to geometrical dimensions and viscoelastic coefficients of the pipe via the generalized Kelvin-Voigt model. FRFs of liquid pressures at the locations under a hypothetical no-leakage condition are computed according to the FRF of transient discharge and the frequency-dependent wave speed. By using the matched-field processing (MFP) method, which maximizes the signal-to-noise ratio in detection, the leakage location is estimated from the FRFs of liquid pressures.
Type:
Grant
Filed:
May 26, 2020
Date of Patent:
November 2, 2021
Assignee:
The Hong Kong University of Science and Technology
Abstract: The present invention discloses a method for detecting the mechanical response of a mechanical component by an organic mechanoresponsive fluorescent material, comprising the following steps of: selecting an organic mechanoresponsive fluorescent material; preparing an organic mechanoresponsive fluorescent material solution; forming a film on a metal surface; calibrating fluorescence intensity and obtaining the fluorescence intensity and distribution in a crack tip area; observing the fluorescence signal generated at cracks to monitor the occurrence of fatigue cracks, and predict a propagation pathway of fatigue cracks by using the fluorescence intensity distribution in the crack tip area.
Type:
Application
Filed:
April 26, 2018
Publication date:
October 28, 2021
Applicants:
Tianjin University, The Hong Kong University of Science and Technology
Abstract: The present application provides a Capillary number-based method of isolating circulating rare cells from a blood sample from a subject using filtration parameters determined based on the measurement of hemorheological parameters of the sample. The present application also provides a method for determining filtration parameters in a microfluidic elasto-filtration process for isolating circulating rare cells from a blood sample from a subject. The present application further provides a device for isolating circulating rare cells from a blood sample from a subject and a non-transitory computer storage medium for performing methods described in the present application.
Type:
Grant
Filed:
April 26, 2017
Date of Patent:
August 24, 2021
Assignee:
The Hong Kong University of Science and Technology
Abstract: Provided is an integrated circuit structure and a method for manufacturing the same. The integrated circuit structure comprises a substrate; a plurality of interconnecting structures on the substrate, each of the interconnecting structures comprises side surfaces and a top surface, the side surfaces directly define air gaps therebetween isolating the interconnecting structures from each other; and a planar protective layer on top of the plurality of interconnecting structures covering all of the air gaps. The protective layer comprises a sheltering film and a supporting film.
Type:
Grant
Filed:
February 28, 2018
Date of Patent:
August 17, 2021
Assignee:
The Hong Kong University of Science and Technology
Inventors:
Salahuddin Raju, Man Sun John Chan, Clarissa Cyrilla Prawoto
Abstract: Methods, systems and storage medium for separating a target signal from noise are disclosed. A method comprises providing a plurality of input signals, each of the plurality of input signals comprising the target signal; synchronizing the plurality of input signals; and separating the plurality of synchronized input signals into the target signal and the noise.
Type:
Application
Filed:
August 15, 2016
Publication date:
July 8, 2021
Applicant:
The Hong Kong University of Science and Technology
Abstract: A system to produce reactive oxidative species in a fluid medium containing a source of Cl(I) by irradiating a solid photocatalyst suspended in the fluid medium or residing on a surface that is contactable by the fluid with electromagnetic radiation. The electromagnetic radiation can be in the UV, near-UV, visible, or near-IR consistent with the photocatalyst employed. The source of Cl(I) in certain embodiments is Cl2, HOCl, or H2NCl. The photocatalyst is g-C3N4, TiO2, BBiOBr, or any other solid insoluble photocatalyst.
Type:
Grant
Filed:
November 26, 2019
Date of Patent:
June 29, 2021
Assignee:
The Hong Kong University of Science and Technology
Abstract: A meta-solid-state battery includes a first layer disposed on a first current collector, a second layer disposed on a second current collector, and third layer disposed between the first layer and the second layer. The first layer and the second layer are the cathode and anode electrodes. The third layer includes a first meta-solid-state electrolyte material. Each of the cathode and anode electrodes contain: an active material in an amount ranging from approximately 70% to 99.98% by weight, a carbon additive in an amount ranging from approximately 0.010% to 20% by weight, and a second meta-solid-state electrolyte material in an amount ranging from approximately 0.010% to 10% by weight. The first and second meta-solid-state electrolyte material include a gel polymer.
Type:
Grant
Filed:
May 3, 2016
Date of Patent:
June 22, 2021
Assignee:
The Hong Kong University of Science and Technology
Inventors:
Matthew Ming-Fai Yuen, Francesco Ciucci, Stephen Chin-To Kwok, Kan Kan Yeung
Abstract: Provided herein are organic long persistent luminescence compositions and methods of use and preparation thereof and articles comprising the same.
Type:
Grant
Filed:
May 22, 2020
Date of Patent:
June 15, 2021
Assignee:
The Hong Kong University of Science and Technology
Inventors:
Benzhong Tang, Parvej Alam, Nelson Lik Ching Leung
Abstract: A low birefringence ferroelectric liquid crystal (FLC) mixture composed of at least two components shows birefringence in the range 0.05 to 0.14, which is suitable for the modern display and photonic devices. The cell gap can be tuned from 1.5 ?m to 4 ?m to reduces the fabrication complexity and chromatic distortion by electro-optical modulation. The FLC mixtures can be employed in a wide temperature range. The characteristics of the said FLC mixture can be tuned by tuning the concentration of the constituents of the mixture. The helical pitch of the FLC mixtures can be varied from 100 nm to 10 ?m. A smectic tilt angle can be varied between 17° to 45° and the spontaneous polarization can be tuned over a wide range to meet requirements of different electro-optical modes, and the FLC mixture is applicable for a wide variety of electro-optical effects.
Type:
Grant
Filed:
January 30, 2018
Date of Patent:
May 25, 2021
Assignee:
The Hong Kong University of Science and Technology
Inventors:
Valerii Vladimirovich Vashchenko, Evgenii Pavlovich Pozhidaev, Abhishek Kumar Srivastava, Vladimir Grigorievich Chigrinov, Hoi Sing Kwok
Abstract: Methods and systems for generating non-diffracting light sheets for multicolor fluorescence microscopy are disclosed. A method for generating a non-diffracting light patterned Bessel sheet comprises transmitting an input light beam through a Fourier transform lens the input light beam has a spatial intensity pattern at a first plane, and a Fourier plane is formed after the Fourier transform lens to obtain a first light beam; transmitting the first light beam through an annulus mask to obtain a second light beam; and transmitting the second light beam through an excitation objective lens to form a non-diffracting patterned light sheet. A method for generating a non-diffracting light line Bessel sheet comprises transmitting an input light beam at a first lane through an annulus mask to obtain a first light beam; and transmitting the first light beam through an excitation objective lens to form a non-diffracting Bessel light sheet.
Type:
Grant
Filed:
February 2, 2016
Date of Patent:
March 9, 2021
Assignee:
The Hong Kong University of Science and Technology
Inventors:
Ming Tak Michael Loy, Shengwang Du, Teng Zhao, Sze Cheung Lau, Ying Wang, Yumian Su
Abstract: The present invention provides new, fully human EphA4 monoclonal antibodies with distinct binding characteristics. Also disclosed are antigen binding fragments of these antibodies, bispecific forms of these antibodies, and conjugates of these antibodies. In addition, nucleic acids encoding these antibodies, antigen binding fragments, bispecific antibodies and conjugates are disclosed. These monoclonal antibodies, antigen binding fragments, bispecific antibodies, conjugates, nucleic acids and vectors are of use for identifying and treating a subject with a disease or condition involving abnormal EphA4-mediated signaling.
Type:
Grant
Filed:
July 31, 2015
Date of Patent:
March 2, 2021
Assignees:
The Hong Kong University of Science and Technology, THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES