Abstract: The subject invention pertains to the rapid amplification and real-time monitoring of nucleic acid sequences at a constant temperature. Specifically, fluorescent or electroactive-labeled loop probes and primers are designed to be specific to identified regions of a target nucleic acid sequences and subsequently amplify and permit the identification of the presence of the target sequence. In this method, a DNA polymerase with no 5? to 3? exonuclease activity is added to extend the primers and probes, while a nicking endonuclease is added to specifically identify the amplified nucleic acid product and cleave the label from the loop probe-extended DNA duplex.

Abstract: A fluorescent probe can include a compound exhibiting aggregation-induced emission (AIE). The probe can be used for selectively staining mitochondria and lipid droplets and detecting esterase activity. The probe includes an acetoxyl group which can be recognized by esterase in an esterase activity assay. As enzyme activity can reflect cell viability, the probe can be useful in cell viability detection. In addition, the probe includes a cationic moiety to target mitochondria and a lipophilic moiety that can target lipid droplets. A calculated log P value of the lipophilic moiety can be larger than 5.

Abstract: A PAM-4 receiver with jitter compensation clock and data recovery is provided. The receiver includes a first-order delay-locked loop (DLL) which employs a bang-bang phase detector (BBPD) and a voltage-controlled delay line (VCDL) circuit supporting 40 MHz jitter tracking bandwidth and static phase skew elimination. A second-order wideband phase-locked loop (WBPLL) using the ¼-rate reference clock provides multi-phase clock generation with low input-to-output latency. To suppress the consequent jitter transfer, a jitter compensation circuit (JCC) acquires the jitter transfer amplitude and frequency information by detecting the DLL loop filter voltage (VLF(s)) signal, and generates an inverted loop filter voltage signal, denoted as VLFINV(s). The VLFINV(s) modulates a group of complementary VCDLs (C-VCDLs) to attenuate the jitter transfer on both recovered clock and data. With the provided receiver, a jitter compensation ratio up to 60% can be supported from DC to 4 MHz, with a ?3-dB corner frequency of 40 MHz.

Abstract: The present invention provides a signal fusion system that is a probabilistic system fusing an arbitrary combination of heterogeneous signals for determining the location of electronic devices. The system includes a signal sampling device for detecting one or more signals emitted by an electronic device to be located, including geolocation signals, WiFi signals, Bluetooth signals, 4G communication signals, 5G communication signals, geomagnetism signals, or inertial navigation system signals (INS). A likelihood processor cooperates with the signal sampling device to receive information about selected sampled signals, and creates a grid of reference points for an interested area in which the electronic device may be located. The likelihood processor independently computes, for each selected sampled signal, a location likelihood that is a probability of observing the sampled signal given that the electronic device is located at different reference points in the grid.

Abstract: The present disclosure relates to a method for growing III-V compound semiconductors on silicon-on-insulators. Starting from {111}-oriented Si seed surfaces between a buried oxide layer and a patterned mask layer, the III-V compound semiconductor is grown within lateral trenches by metal organic chemical vapor deposition such that the non-defective portion of the III-V compound semiconductor formed on the buried oxide layer is substantially free of crystalline defects and has high crystalline quality.

Abstract: A fluorescent compound for acid detection is strongly emissive in the solid state and can aggregate in the presence of an acid. As such, a fluorescent intensity emitted from the compound can be enhanced from an original intensity level in the presence of an acid. The fluorescent compound can emit an enhanced fluorescent intensity in the presence of an ultra-low acid concentration, for example, a concentration of at least about 10?20 M.

Abstract: A gas sensor array comprises a plurality of metal decorated metal oxide film based on three-dimensional nanostructured templates, each including a porous anodized aluminum oxide (AAO) template and a plurality of metal decorated metal oxide films. The porous AAO substrate has a top surface with top gold electrodes, a bottom surface with bottom gold electrodes and a plurality of pores. Each pore has an interior wall and two openings located on the top surface and the bottom surface respectively for allowing air to enter into the pore. Each metal-decorated metal oxide film comprises a metal oxide film and metal decoration particles. The metal oxide film has an internal surface attaching on a respective interior wall and an external surf-ace being decorated with the metal particles. Each decoration metal is different to provide different sensitivities in response to an environmental gas.

Abstract: Provided herein are methods, kits, and devices related to genetic variations of neurological disorders. For example, methods, kits, and devices for using such genetic variations to assess susceptibility of developing Alzheimer's disease.

Abstract: An aerogel is formed by preparing metal-organic framework (MOF) aerogels by preparing a porous solid comprising a metal precursor for the metal-organic framework (MOF) aerogels, and transforming the metal precursor into the MOF by reacting the porous solid with organic ligands mixed with a solvent. The solvent is then removed by supercritical extraction and drying.

Abstract: Structures, devices and methods are provided for forming an interface protection layer (204) adjacent to a fully or partially recessed gate structure (202) of a group III nitride, a metal-insulator-semiconductor high-electron-mobility transistor (MIS-HEMT) device or a metal-insulator-semiconductor field-effect transistor (MIS-FET) device, and forming agate dielectric (114) disposed the interface protection layer (204).

Abstract: A flexible display device that can conform to complex curved surfaces, and methods for manufacturing said display device, are disclosed herein. The display device utilizes a Miura-ori origami structure that, in a folded or at least partially folded configuration, is able to conform to complex curved surfaces. The Miura-ori structure involves folding a two-dimensional substrate in accordance with crease lines comprising a tessellation of parallelograms. Each cell of the tessellation pattern can include one or more luminous elements (LEDs, OLEDs, etc.) bonded to circuit elements embedded within the flexible substrate (e.g., Parylene-C).

Abstract: A flexible electronic device (SED) that can conform to a three-dimensional structure, and methods for manufacturing the SED, are disclosed herein. The SED comprises a flexible substrate which is modified in accordance with a folding pattern. The flexible substrate can be folded or unfolded along crease lines of the folding pattern, and the largest deformations of the substrate are localized at the crease lines. Various functional components of the SED are positioned on rigid regions of the substrate defined by the folding pattern. Such that the various functional components are protected from large deformations due to a folding or unfolding process, ensuring good performance of the functional components.

Abstract: A method for preparing optical fibers formed with high-particle-coated porous polymeric outer coating layer is provided. The method includes preparing a coating suspension solution by dispersing a plurality of particles into an organic solvent system, immersing one or more optical fibers into the coating suspension solution, removing the one or more optical fibers from the coating suspension solution to form high-particle-coated porous polymeric outer coating layer after drying. Concentrations and compositions of the particles in the coating suspension solution, concentrations and compositions of the organic solvent system, the period of time of immersing, or the external environment are adjusted such that the optical fibers is formed with high-particle-coated polymeric outer coating layers having desirable coating masses, coating thicknesses, or coating morphologies.

Abstract: Graphene oxide aerogel beads (GOABs) are formed that have a core/shell structure where a smooth shell covers a multi-layer core. The smooth shell and the layers of the multilayer core comprise graphene oxide or reduced graphene oxide. The GOABs can include a phase-change material encapsulated within the multi-layer core. The GOABs can be combined or decorated with Fe3O4 nanoparticles or MoS2 microflakes for various applications. The GOABs are formed from aqueous slurries of graphene oxide that is extruded as drops into an aqueous solution of a coagulant where GOABs are formed. The GOABs are washed and freeze dried, after which, the GOABs can be reduced as desired by chemical or thermal means. Impregnation can be carried out with the phase-change material.

Abstract: The antimicrobial coating material for surface coating is formed from encapsulated biocides. The biocides include at least one antimicrobial component. The biocides are encapsulated in inorganic-organic shells which are permeable to the biocides. The organic materials may include at least one nonionic polymer. The inorganic-organic shells encapsulate and contain the biocides to form capsule structures for storage and release of the biocides. The capsule structures may be single capsules or capsule-in-capsule structures. The inorganic materials may be present in a concentration of 0.5-95 wt % of the inorganic-organic shells. Alternatively, the inorganic materials may be present in a concentration of 5-60 wt %. The inorganic materials and the organic materials are each intermixed, with respect to one another, in structures of the inorganic-organic shells. These structures may be an attachment structure, a hybrid structure or a multi-layered structure.

Abstract: A method for treating cancer by using an agent which is capable of inhibiting the functionality of the MCM complex, a heterohexameric ring formed from six subunits, in the process of DNA replication and a method of screening for such agents by detecting the locations and functions of the MCM subunits, such as hMcm2 and hMcm6, in cells treated with candidate compounds.

Abstract: A shadow mask for patterned vapor deposition of an organic light-emitting diode (OLED) material includes a ceramic membrane under tensile stress with a plurality of through-apertures forming an aperture array through which a vaporized deposition material can pass. A multilayer peripheral support is attached to a rear surface with a hollow portion beneath the aperture array. A compressively-stressed interlayer balances the tensile stress of the ceramic membrane. A shadow mask module with multiple shadow masks is also provided and includes a rigid carrier having plural windows with a shadow mask positioned in each window. To make the module, shadow mask blanks are affixed to each carrier window followed by etching of apertures and support layers. In this way extremely flat masks with precise aperture patterns are formed.

Abstract: A method for fabricating a thick crack-free dielectric film on a wafer for device fabrication is disclosed herein. A stress-release pattern is fabricated in an oxide layer of the wafer, which surrounds a number of device regions. The stress-release pattern comprises a plurality of recessions, which are spaced periodically along at least one direction. The plurality of recessions interrupt the continuous film during the dielectric film deposition, to prevent cracks from forming in the dielectric film and propagating into the device regions. Such that, a thick crack-free dielectric film can be achieved in the device regions, which are formed by patterning the dielectric layer. Furthermore, conditions of the dielectric film deposition process can be tuned to ensure quality of the deposited dielectric film. Still further, a plurality of deposition runs may be performed to deposit the thick crack-free dielectric film.

Abstract: A VSR approach with temporal consistency using generative adversarial networks (VistGAN) that requires only the training HR video sequence to generate the HR/LR video frame pairs, instead of the pre-artificial-synthesized HR/LR video frame pairs, for training. By this unsupervised learning method, the encoder degrades the input HR video frames of a training HR video sequence to their LR counterparts, and the decoder seeks to recover the original HR video frames from the LR video frames. To improve the temporal consistency the unsupervised learning method provides a sliding window that explores the temporal correlation in both HR and LR domains. It keeps the temporal consistent and also fully utilizes high-frequency details from the last-generated reconstructed HR video frame.

Abstract: Provided herein are aggregation-induced emission luminogens, methods of preparation and use thereof, and devices and sensors comprising the same. The aggregation-induced emission luminogens can exhibit multi-stimuli responsive emissions.