Patents Assigned to The Ideal Wilson Medical Center
  • Assay for vitamin B.sub.12
    Patent number: 4355018
    Abstract: A highly specific assay for plasma vitamin B.sub.12 levels in humans is disclosed. The assay employs intrinsic factor preparations obtained from mouse or rat stomachs, which intrinsic factors are free of R-protein and thus react specifically with vitamin B.sub.12 in a competitive binding assay. Detection of vitamin B.sub.12 levels is utilized in the diagnosis of several clinical disorders, such as pernicious anemia, a disease state which results in reduced circulating levels of vitamin B.sub.12 in the blood.
    Type: Grant
    Filed: May 21, 1980
    Date of Patent: October 19, 1982
    Assignees: Hoffmann-La Roche Inc., The Ideal Wilson Medical Center
    Inventors: Hans J. Hansen, Gustavo Reynoso