Patents Assigned to The Institute for Pharmaceutical Discovery, Inc.
  • Substituted heteroarylalkanoic acids
    Patent number: 7361671
    Abstract: Disclosed are substituted heteroarylalkanoic acids acids of the following formula D-A-C(O)R?, where D, A, and R? are defined herein. These compounds are useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: April 22, 2008
    Assignee: The Institute for Pharmaceutical Discovery, Inc.
    Inventors: Michael C. Van Zandt, Leo Geraci
  • Method of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substitute indolealkanoic acids
    Patent number: 6964980
    Abstract: Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in need of such treatment. Also disclosed are such compounds useful in the treatment of angiogenesis, hyperglycemia, hyperlipidemia and chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: November 15, 2005
    Assignee: The Institute for Pharmaceutical Discovery, Inc.
    Inventors: Janet Sredy, Jorge Jacot
  • Method of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substitute indolealkanoic acids
    Publication number: 20030216452
    Abstract: Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in need of such treatment. Also disclosed are such compounds useful in the treatment of angiogenesis, hyperglycemia, hyperlipidemia and chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds.
    Type: Application
    Filed: March 26, 2003
    Publication date: November 20, 2003
    Applicant: The Institute for Pharmaceutical Discovery, Inc.
    Inventors: Janet Sredy, Jorge Jacot
  • Substituted heteroarylalkanoic acids
    Publication number: 20030166668
    Abstract: Disclosed are substituted heteroarylalkanoic acids acids of the following formula D-A-C(O)R′, where D, A, and R′ are defined herein. These compounds are useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.
    Type: Application
    Filed: November 14, 2002
    Publication date: September 4, 2003
    Applicant: The Institutes for Pharmaceutical Discovery, Inc. A Corporation of the State of Delaware
    Inventors: Michael C. Van Zandt, Leo Geraci
  • Substituted indolealkanoic acids
    Patent number: 6214991
    Abstract: Disclosed are substituted indolealkanoic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.
    Type: Grant
    Filed: March 31, 1999
    Date of Patent: April 10, 2001
    Assignee: The Institute for Pharmaceutical Discovery, Inc.
    Inventors: Michael Lee Jones, David Gunn, John Howard Jones, Michael C. Van Zandt