Patents Assigned to THE INSTITUTE OF BIOLOGICAL RESOURCES
  • Patent number: 12000814
    Abstract: The present disclosure provides an apparatus and method for producing a policosanol having a specific chromatographic fingerprint. The apparatus of the present disclosure has a feed tank and receiving tanks which are connected to a vacuum system. The method of the present disclosure is carried out by a high vacuum rectification process and includes: firstly, feeding a saponified crude alkanol into a melting tank in which the material is melted and then flows into the feed tank, and then injecting the material into a rectifying still using a delivery pump, followed by first rectification under vacuum condition and sequential collection of fractions at different phases from the tower top and stillage residue from the tower bottom; and after the completion of the rectification of the first batch crude product, carrying out second feeding on the basis of consistent vacuum in the feed tank and the rectifying tower.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: June 4, 2024
    Assignee: Institute of Biological Resources, Jiangxi Academy of Sciences
    Inventors: Lichuang Cai, Jianping Liu, Kexian Ouyang, Xiongchang Guo, Yue Tu
  • Patent number: 11000039
    Abstract: A method for controlling nematode includes treating a plant or soil with a composition comprising a grammicin compound of Formula 1 or an agriculturally acceptable salt thereof. The grammicin compound may be isolated from a Xylaria grammica strain so that it is harmless to a human body, does not cause any environmental contamination, and exhibits an excellent control activity against root knot nematodes. Thus, it can be advantageously used for developing an environment-friendly natural nematicide and production of a high value-added organic agricultural product.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: May 11, 2021
    Assignees: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY, NATIONAL INSTITUTE OF BIOLOGICAL RESOURCES
    Inventors: Jin-Cheol Kim, Tae Yoon Kim, Ja Yeong Jang, Won-Jae Chi, Chang Hwan Bae, Joo Hong Yeo
  • Patent number: 10980242
    Abstract: Xylaria grammica EL 000614 strain has a nematicidal activity against root knot nematode. A method for controlling root knot nematode includes treating a crop, a crop seed, or a field for cultivation with a nematicidal microorganism formulation. The method has very little possibility of having a problem related to environmental contamination, and exhibits a high mortality and activity of inhibiting egg hatching for sweet potato root knot nematode (M. incognita). It is expected that the strain can be very advantageously used as an innovative biological control agent which enables prevention of problems associated with environmental contamination.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: April 20, 2021
    Assignees: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY, NATIONAL INSTITUTE OF BIOLOGICAL RESOURCES
    Inventors: Jin-Cheol Kim, Tae Yoon Kim, Ja Yeong Jang, Nan Hee Yu, Won-Jae Chi, Chang Hwan Bae, Joo Hong Yeo
  • Patent number: 9555094
    Abstract: The present invention relates to a nucleic acid for vaccine that has undergone codon optimization for expression in Bombyx mori, a vector comprising the nucleic acid, Bombyx mori comprising the vector, and a method for producing a vaccine in which they are used.
    Type: Grant
    Filed: July 23, 2013
    Date of Patent: January 31, 2017
    Assignee: The Institute of Biological Resources
    Inventors: Kazumichi Kuroda, Shigeo Sugita, Kuniaki Nerome, Reiko Nerome
  • Publication number: 20140370131
    Abstract: The present invention relates to a pharmaceutical composition and food composition comprising Nelumbo nucifera seed extract as an active ingredient for the protection of brain nerve cells. Particularly, the composition is characterized by having an activity of removing reactive oxygen species (ROS) or an antioxidant activity. More particularly, the antioxidant activity is characterized by the activity of removing 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals or the activity of removing hydrogen peroxide (H2O2). Also, the present invention is extracted from a natural substance and is thus safe for the human body and provides fundamental data to the food and pharmaceutical fields, which use products derived from natural substances.
    Type: Application
    Filed: January 18, 2013
    Publication date: December 18, 2014
    Applicant: NATIONAL INSTITUTE BIOLOGICAL RESOURCES
    Inventors: Eun Sil Kim, Choong Je Ma, Kyounghee Oh
  • Publication number: 20130236580
    Abstract: An anti-influenza virus agent, an anti-RS virus agent, or an anti-immunodeficiency virus agent, which comprises components originated from plants and which has excellent infectivity-inhibitory effect and proliferation-inhibitory effect against influenza viruses, RS viruses and immunodeficiency viruses. The anti-influenza virus agent, anti-RS virus agent or anti-immunodeficiency virus agent of the present invention comprises an extract derived from, or dry powder of the leaves of a plant belonging to the family Betulaceae and/or a plant belonging to the family Meliaceae.
    Type: Application
    Filed: April 29, 2013
    Publication date: September 12, 2013
    Applicant: THE INSTITUTE OF BIOLOGICAL RESOURCES
    Inventor: Kuniaki Nerome