Patents Assigned to The Institute Pasteur
  • GENE REPAIR INVOLVING IN VIVO EXCISION OF TARGETING DNA
    Publication number: 20120165400
    Abstract: Methods of modifying, repairing, attenuating and inactivating a gene or other chromosomal DNA in a cell are disclosed. Also disclosed are methods of treating or prophylaxis of a genetic disease in an individual in need thereof.
    Type: Application
    Filed: May 5, 2011
    Publication date: June 28, 2012
    Applicants: The Children's Medical Center Corporation, The Institute Pasteur
    Inventors: André Choulika, Richard C. Mulligan
  • Gene repair involving in vivo excision of targeting DNA
    Patent number: 7960525
    Abstract: Methods of modifying, repairing, attenuating and inactivating a gene or other chromosomal DNA in a cell are disclosed. Also disclosed are methods of treating or prophylaxis of a genetic disease in an individual in need thereof.
    Type: Grant
    Filed: September 25, 2007
    Date of Patent: June 14, 2011
    Assignees: The Institute Pasteur, The Children's Medical Center Corporation
    Inventors: André Choulika, Richard C. Mulligan
  • Gene repair involving in vivo excision of targeting DNA
    Publication number: 20090060896
    Abstract: Methods of modifying, repairing, attenuating and inactivating a gene or other chromosomal DNA in a cell are disclosed. Also disclosed are methods of treating or prophylaxis of a genetic disease in an individual in need thereof.
    Type: Application
    Filed: September 25, 2007
    Publication date: March 5, 2009
    Applicants: THE CHILDREN'S MEDICAL CENTER CORPORATION, THE INSTITUTE PASTEUR
    Inventors: Andre Choulika, Richard C. Mulligan
  • Gene repair involving in vivo excision of targeting DNA
    Patent number: 7285538
    Abstract: Methods of modifying, repairing, attenuating and inactivating a gene or other chromosomal DNA in a cell are disclosed. Also disclosed are methods of treating or prophylaxis of a genetic disease in an individual in need thereof.
    Type: Grant
    Filed: January 2, 2003
    Date of Patent: October 23, 2007
    Assignees: The Children's Medical Center Corporation, The Institute Pasteur
    Inventors: André Choulika, Richard C. Mulligan
  • Gene repair involving the induction of double-stranded DNA cleavage at a chromosomal target site
    Publication number: 20040019002
    Abstract: Methods of modifying, repairing, attenuating and inactivating a gene or other chromosomal DNA in a cell are disclosed. Also disclosed are methods of treating or prophylaxis of a genetic disease in an individual in need thereof. Further disclosed are chimeric restriction endonucleases.
    Type: Application
    Filed: January 6, 2003
    Publication date: January 29, 2004
    Applicants: The Children's Medical Center Corporation, The Institute Pasteur
    Inventors: Andre Choulika, Richard C. Mulligan