Abstract: The present invention provides cell-based assays, including high throughput cell-based assays, for identification of candidate therapeutic agents with the ability to inhibit microglial activation in vivo in response to different ligands.
Type:
Grant
Filed:
April 2, 2018
Date of Patent:
August 24, 2021
Assignees:
The J. David Gladstone Insitutes, The Regents of the University of California
Inventors:
Katerina Akassoglou, Michelle Arkin, Kean-Hooi Ang, Anke Meyer-Franke, Christopher Wilson