Patents Assigned to THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLAD
  • METHODS FOR TREATMENT OF RETINAL DISEASE BY PHOTORECEPTOR GENE EXPRESSION MODULATION
    Publication number: 20190381047
    Abstract: Methods for decreasing rod gene expression in a retina, methods for decreasing the protein products expressed by rod genes in a retina, methods for treating a disease or condition treatable by decreasing rod gene expression or their protein products in a retina, and methods for treating a retinal disease in a subject.
    Type: Application
    Filed: June 20, 2019
    Publication date: December 19, 2019
    Applicants: University of Washington, The J. David Gladstone Institutes, a Testamentary Trust Established Under the Will of J. David Glads
    Inventors: Thomas A. Reh, Paul Nakamura, Sheng Ding
  • METHODS FOR TREATMENT OF RETINAL DISEASE BY PHOTORECEPTOR GENE EXPRESSION MODULATION
    Publication number: 20180125847
    Abstract: Methods for decreasing rod gene expression in a retina, methods for decreasing the protein products expressed by rod genes in a retina, methods for treating a disease or condition treatable by decreasing rod gene expression or their protein products in a retina, and methods for treating a retinal disease in a subject.
    Type: Application
    Filed: March 28, 2016
    Publication date: May 10, 2018
    Applicants: University of Washington, The J. David Gladstone Institutes, a Testamentary Trust Established Under the Will of J. David Glads
    Inventors: Thomas A. Reh, Paul Nakamura, Sheng Ding
  • SUBSTITUTED BENZOXAZINE AND RELATED COMPOUNDS
    Publication number: 20160326123
    Abstract: The present invention relates to compounds including but not limited to of any one of formulas Ia, Ib, IIa, IIb, IIIa, IIIb, and IV to VI, VIIa, VIIb, VIIIa, VIIIb and VIIIc as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.
    Type: Application
    Filed: January 8, 2015
    Publication date: November 10, 2016
    Applicant: THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLAD
    Inventors: Andrey S. Tsvetkov, Steven M. Finkbeiner, Michael A. Pleiss, Robert Greenhouse
  • GENERATING HEPATOCYTES
    Publication number: 20150175962
    Abstract: Compositions and methods are described herein for inducing reprogramming of non-pluripotent cells across lineage and differentiation boundaries to generate endodermal progenitor cells and hepatocytes. Compositions and methods for expansion of endodermal progenitor cells without loss of phenotype are also described herein.
    Type: Application
    Filed: December 20, 2014
    Publication date: June 25, 2015
    Applicants: The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Glads, The Regents of the University of California
    Inventors: Saiyong Zhu, Sheng Ding, Holger Willenbring, Milad Rezvani, Jack Harbell