Patents Assigned to The J. David Gladstone Institutes, A Testamentary Trust Established Under the Will of Will of J. Dav
  • ENGINEERED CARDIOMYOCYTES AND USES THREOF
    Publication number: 20200308546
    Abstract: The present disclosure provides the development of engineered cardiomyocytes having mutations in transcription factor involved in vivo with cardiac development and/or function. These cell populations comprise mutations that are associated with deleterious effects in vivo in mammals. The mutations of the engineered cardiomyocytes of the disclosure thus are rationally designed based on demonstrated physiological effects in mammals, e.g., mice or humans.
    Type: Application
    Filed: June 27, 2017
    Publication date: October 1, 2020
    Applicant: The J. David Gladstone Institutes, A Testamentary Trust Established Under the Will of Will of J. Dav
    Inventors: Deepak SRIVASTAVA, Yen-Sin ANG