Abstract: The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
Type:
Application
Filed:
December 20, 2021
Publication date:
April 14, 2022
Applicant:
The Kennedy Trust for Rheumatology Research
Inventors:
Mervyn Maze, Marc Feldmann, Noccolo Terrando, Mario Cibelli, Daqing Ma, Michael Fertleman, Jagdeep Nanchahal
Abstract: The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
Type:
Grant
Filed:
October 23, 2019
Date of Patent:
January 11, 2022
Assignee:
THE KENNEDY TRUST FOR RHEUMATOLOGY RESEARCH
Inventors:
Mervyn Maze, Marc Feldmann, Noccolo Terrando, Mario Cibelli, Daqing Ma, Michael Fertleman, Jagdeep Nanchahal
Abstract: The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
Type:
Application
Filed:
October 23, 2019
Publication date:
April 23, 2020
Applicant:
The Kennedy Trust for Rheumatology Research
Inventors:
Mervyn Maze, Marc Feldmann, Noccolo Terrando, Mario Cibelli, Daqing Ma, Michael Fertleman