Patents Assigned to The Massachusetts Institute Technology
  • Patent number: 8625840
    Abstract: Described are a method and an apparatus for generating a forecast weather image such as a forecast weather radar image. The method uses filters to approximate viscous alignment and to thereby determine displacement fields having meaningful structure. In various embodiments a power-law energy spectrum is utilized for deformations in the displacement field through the application of a set of Gabor filters. The Gabor filters are applied in a sequential manner to gradient error images and values of modes of motions corresponding to the Gabor filters are determined. The values are used to generate the displacement field which can then be applied to an existing weather image to generate a forecast weather image.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: January 7, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Srinivas Ravela, William J. Dupree, Timothy R. Langlois, Marilyn M. Wolfson, Christopher M. Yang
  • Patent number: 8625075
    Abstract: Systems and methods related to the generation of interference patterns using electromagnetic radiation are generally described. Some embodiments are directed to the use of such systems and methods to perform interference lithography.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: January 7, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Karl K. Berggren, Hasan Korre, Corey P. Fucetola
  • Publication number: 20140004592
    Abstract: One aspect of the invention is a salt comprising guanidinium groups, as shown in formula I. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula II. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula III. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula IV. Yet another aspect of the invention is a salt comprising guanidinium groups, as shown in formula I, II, III, and IV further comprising independently for each occurrence citrate, phosphate, or sulfate anion. Also disclosed are compositions comprising a protein and a salt comprising guanidinium groups, as shown in formula I, II, III, and IV. Also provided are methods of increasing shelf life of an aqueous solution of a protein and decreasing the amount of protein aggregation in an aqueous solution of a protein.
    Type: Application
    Filed: November 11, 2011
    Publication date: January 2, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Bernhardt L. Trout, II, Diwakar Shukla, Curtiss P. Schneider
  • Publication number: 20140003338
    Abstract: A distributed wireless communication system includes multiple access points, each with one or more antennas. The access points do not necessarily have synchronized transmitting and receiving radio frequency oscillators. Approaches to channel estimation between the access points and one or more wireless clients account for the lack of synchronization, and do not necessarily require capabilities at the clients that go beyond required or optional features of standard wireless Ethernet (e.g., 802.11n, 802.11g, or 802.11a), thereby supporting “legacy” clients while supporting high data throughput approaches that provide coherent transmission from the multiple antenna of the access points.
    Type: Application
    Filed: October 5, 2012
    Publication date: January 2, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Hariharan Shankar Rahul, Swarun Suresh Kumar, Dina Katabi
  • Publication number: 20140003193
    Abstract: A system for providing collision avoidance in underwater vehicles contains a spectral analysis module for determining expectation value of acoustic (incoherent) intensity. The system also contains an intercept time estimation module for: receiving continuous time series of a current incoherent acoustic intensity and low pass filtering the time series of the current incoherent acoustic intensity; estimating temporal intensity rate of change; determining an estimated time to collision for an approaching source; and performing statistical regression analysis resulting in an estimated time of potential collision and an uncertainty measure.
    Type: Application
    Filed: June 28, 2012
    Publication date: January 2, 2014
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Henrik Schmidt, Michael Benjamin
  • Publication number: 20140004503
    Abstract: Trapping devices and methods are provided for capturing a medical analyte, in blood or another biological fluid. The device may include a structural substrate and a binding agent, such as an antibody, affixed to the structural substrate, wherein the binding agent is capable of binding or attaching with a medical analyte, such as a viral particle, and the device is configured for placement in a biological cavity or vessel (containing a biological fluid) in a patient. The trapping device, which may be in a twisted coil shape, is configured to trap at least some of the medical analyte, such a viral particle, present in the biological fluid. The method may include deploying a trapping device into the patient's blood vessel; after a period following the deployment, removing the trapping device from the biological cavity or blood vessel; and then analyzing the trapping device for the presence of the medical analyte.
    Type: Application
    Filed: December 30, 2011
    Publication date: January 2, 2014
    Applicants: LAHEY CLINIC FOUNDATION, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Michael J. Cima, Gregory J. Ekchian, Christophoros C. Vassiliou, Vincent H. Liu, Christoph Wald, Sebastian Flacke, Fredric D. Gordon
  • Publication number: 20140002613
    Abstract: The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements of hardware, and processing techniques that can be used to capture these thickness measurements and obtain three-dimensional images of the target surface in a variety of imaging contexts. This includes general techniques for imaging interior/concave surfaces as well as exterior/convex surfaces, as well as specific adaptations of these techniques to imaging ear canals, human dentition, and so forth.
    Type: Application
    Filed: September 5, 2013
    Publication date: January 2, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Douglas P. Hart, Federico Frigerio, Davide M. Marini
  • Publication number: 20140000688
    Abstract: A method of a general biological approach to synthesizing compact nanotubes using a biological template is described.
    Type: Application
    Filed: June 10, 2013
    Publication date: January 2, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Xiangnan Dang, Hyunjung Yi, Angela M. Belcher, Paula T. Hammond
  • Patent number: 8617819
    Abstract: The present invention generally relates to organic polymers able to participate in an analyte-recognition process, where an analyte facilitates an energy transfer between an energy donor and an energy acceptor. Certain embodiments of the invention make use of fluorescent conjugated polymers, such as poly(phenylene ethynylene)s and other polymers comprising pi-conjugated backbones. For example, one aspect of the invention provides a fluorescent conjugated polymer and an indicator that can interact with each other in the presence of an analyte to produce an emissive signal. In some cases, the interaction may include energy exchange mechanisms, such as Dexter energy transfer or the strong coupling effect. The interaction of the conjugated polymer and the indicator, in some instances, may be facilitated through specific interactions, such as a protein/carbohydrate interaction, a ligand/receptor interaction, etc.
    Type: Grant
    Filed: September 19, 2005
    Date of Patent: December 31, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, Peter H. Seeberger, Juan Zheng, Matthew D. Disney
  • Patent number: 8619832
    Abstract: Terahertz quantum cascade (QC) devices are disclosed that can operate, e.g., in a range of about 1 THz to about 10 THz. In some embodiments, QC lasers are disclosed in which an optical element (e.g., a lens) is coupled to an output facet of the laser's active region to enhance coupling of the lasing radiation from the active region to an external environment. In other embodiments, terahertz amplifier and tunable terahertz QC lasers are disclosed.
    Type: Grant
    Filed: May 8, 2009
    Date of Patent: December 31, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Qing Hu, Alan Wei Min Lee
  • Patent number: 8619154
    Abstract: The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements of hardware, and processing techniques that can be used to capture these thickness measurements and obtain three-dimensional images of the target surface in a variety of imaging contexts. This includes general techniques for imaging interior/concave surfaces as well as exterior/convex surfaces, as well as specific adaptations of these techniques to imaging ear canals, human dentition, and so forth.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: December 31, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Douglas P. Hart, Federico Frigerio, Davide M. Marini
  • Patent number: 8619358
    Abstract: An optical amplifier on a silicon platform includes a first doped device layer and a second doped device layer. A gain medium is positioned between the first and second doped device layers. The gain medium comprises extrinsic gain materials so as to substantially confine in the gain medium a light signal and allow the optical amplifier to be electrically or optically pumped.
    Type: Grant
    Filed: November 3, 2009
    Date of Patent: December 31, 2013
    Assignees: Massachusetts Institute of Technology, California Institute of Technology, The Board of Trustees of the Leland Stanford Junior University, University of Rochester, Cornell University
    Inventors: Lionel C. Kimerling, Harry Atwater, Mark L. Brongersma, Luca Dal Negro, Thomas L Koch, Philippe Fauchet, Michal Lipson, Jurgen Michel, Carlos Angulo Barrios
  • Patent number: 8617513
    Abstract: One aspect of the present invention relates to mesostructured zeolites. The invention also relates to a method of preparing mesostructured zeolites, as well as using them as cracking catalysts for organic compounds and degradation catalysts for polymers.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: December 31, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Jackie Y. Ying, Javier García-Martínez
  • Publication number: 20130344367
    Abstract: Redox flow devices are described in which at least one of the positive electrode or negative electrode-active materials is a semi-solid or is a condensed ion-storing electroactive material, and in which at least one of the electrode-active materials is transported to and from an assembly at which the electrochemical reaction occurs, producing electrical energy. The electronic conductivity of the semi-solid is increased by the addition of conductive particles to suspensions and/or via the surface modification of the solid in semi-solids (e.g., by coating the solid with a more electron conductive coating material to increase the power of the device). High energy density and high power redox flow devices are disclosed. The redox flow devices described herein can also include one or more inventive design features. In addition, inventive chemistries for use in redox flow devices are also described.
    Type: Application
    Filed: August 26, 2013
    Publication date: December 26, 2013
    Applicants: 24-M Technologies, Inc., Massachusetts Institute of Technology
    Inventors: Yet-Ming Chiang, W. Craig Carter, Bryan Y. Ho, Mihai Duduta, Pimpa Limthongkul
  • Publication number: 20130342895
    Abstract: A method and apparatus for providing a high peak power optical beam. The method includes interleaving pulse trains of different wavelengths and spatially and temporally overlapping the different wavelengths to produce an amplified output beam with very high peak power.
    Type: Application
    Filed: August 22, 2013
    Publication date: December 26, 2013
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Bien Chann, Tso Yee Fan, Antonio Sanchez-Rubio, Steven J. Augst
  • Publication number: 20130341810
    Abstract: In a bubble-column vapor mixture condenser, a fluid source supplies a carrier-gas stream including a condensable fluid in vapor phase. The condensable fluid in liquid form is contained as a bath in a chamber in each stage of the condenser, and the carrier gas is bubbled through the bath to condense the condensable fluid into the bath. Energy from condensation is recovered to a coolant in a conduit that passes through the liquid in the stages of the condenser. The bubble-column vapor mixture condenser can be used, e.g., in a humidification-dehumidification system for purifying a liquid, such as water.
    Type: Application
    Filed: August 26, 2013
    Publication date: December 26, 2013
    Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Prakash Narayan Govindan, Gregory P. Thiel, Ronan K. McGovern, John H. Lienhard, Mostafa Hamed Elsharqawy
  • Publication number: 20130340533
    Abstract: Strain gauge. The gauge includes a substrate and a thin film of overlapping, two-dimensional flakes deposited on the substrate. Structure responsive to conductance across the film is provided whereby a strain induced change in overlap area between neighboring flakes results in a change in conductance across the film. In a preferred embodiment, the two-dimensional flakes are graphene.
    Type: Application
    Filed: November 19, 2012
    Publication date: December 26, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Patent number: 8614612
    Abstract: A superconducting coil includes (a) a plurality of windings of a coil comprising high-temperature superconductors and (b) an electrically conductive channel in which the high-temperature superconductors are mounted. The high-temperature superconductors can comprise at least one of the following: Ba2Sr2Ca1Cu2O8 (2212), Ba2Sr2Ca2Cu3O10 (2223), and YBa2Cu3O7-x (123) superconductor.
    Type: Grant
    Filed: January 17, 2012
    Date of Patent: December 24, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy A. Antaya, Joel Henry Schultz
  • Patent number: 8614092
    Abstract: The invention relates to methods of altering expression of a genomic locus of interest or specifically targeting a genomic locus of interest in an animal cell, which may involve contacting the genomic locus with a non-naturally occurring or engineered composition that includes a deoxyribonucleic acid (DNA) binding polypeptide having a N-terminal capping region, a DNA binding domain comprising at least five or more Transcription activator-like effector (TALE) monomers and at least one or more half-monomers specifically ordered to target the genomic locus of interest, and a C-terminal capping region, wherein the polypeptide includes at least one or more effector domains, and wherein the polypeptide is encoded by and translated from a codon optimized nucleic acid molecule so that the polypeptide preferentially binds to the DNA of the genomic locus.
    Type: Grant
    Filed: December 31, 2012
    Date of Patent: December 24, 2013
    Assignees: The Broad Institute Inc., Massachusetts Institute of Technology
    Inventors: Feng Zhang, Le Cong
  • Patent number: 8614853
    Abstract: A method and apparatus for two-dimensional wavelength beam combining of laser sources. In one example, an external cavity multi-wavelength laser includes an array of laser emitters each producing an optical beam having a specified wavelength, a grating stack comprising a plurality of first-order diffraction gratings arranged linearly in a first dimension, and a dispersive element. The laser further includes a cylindrical telescope that images the optical beams from the array of laser emitters onto the grating stack. A first cylindrical transform lens spatially overlaps the optical beams in a second dimension forming a first region of overlap at the grating stack. A second cylindrical transform lens spatially overlaps the optical beams from the grating stack in the first dimension forming a second region of overlap at the dispersive element. The dispersive element transmits a multi-wavelength output beam comprising the spatially overlapped optical beams from the array of laser emitters.
    Type: Grant
    Filed: March 9, 2010
    Date of Patent: December 24, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Bien Chann, Tso Yee Fan, Antonio Sanchez-Rubio