Abstract: The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities.
Type:
Grant
Filed:
May 2, 2008
Date of Patent:
March 28, 2017
Assignee:
The McLeon Hospital Corporation
Inventors:
Anne M. Cataldo, Peter A. Paskevich, Bruce M. Cohen