Abstract: Systems and methods are provided for performing a calibration “pre-scan” prior to acquiring data using a magnetic resonance imaging (“MRI”) system performing a multi-spectral imaging (“MSI”) acquisition. Information from the calibration scan is used to optimize the scanning and data collection during the MSI scan. As a result, scan times and motion artifacts are reduced. In addition, image resolution can also be increased, thereby improving image quality. As one example, the MSI acquisition can be a MAVRIC acquisition. In general, the calibration data is used to determine the minimum number of spectral bins required to achieve acceptable image quality near a specific metallic implant or device.