Abstract: The present invention related to the provision of genetically modified fungal cells, such as yeast cells with an improved ability for producing and secreting different recombinant proteins. The improved ability is obtained by disruption in intracellular transport between the Golgi and the endosome. In particular embodiments, the disruption is achieved by downregulation or deletion of the gene encoding a Tda3p homolog. The fungal cell and method of the invention would allow for large-scale production of recombinant proteins in fungal cells.

Abstract: A fungal cell is capable of producing high levels of fatty acids and fatty acid-derived products. The fungal cell comprises at least one modification to the endogenous fatty acid metabolism.

Abstract: The present disclosure provides a TiCB—Al seed alloy, a manufacturing method thereof and a heritable aluminum alloy. The TiCB—Al seed alloy includes an Al matrix and TiCB@TiBC seed crystals dispersed on the Al matrix, wherein the TiCB@TiBC seed crystal comprises a core part and a shell part, the core part contains B-doped TiCB, and the shell part covers at least a part of the core part and contains a TiBC ternary phase, wherein the B-doped TiCB refers to a TiCB phase formed by B atoms occupying C vacancies in a TiCx crystal, and the TiBC ternary phase refers to a ternary phase composed of Ti, B and C, wherein x<1.

Abstract: Disclosed are devices and methods for rehydrating plant matter or plant-derived matter and infusing such matter with terpenes and other volatile compounds. In one embodiment, a device to rehydrate and infuse plant or plant-derived matter comprises a first housing portion comprising a central column and a second housing portion configured to be coupled or locked to the first housing portion. The central column of the first housing portion can compromise a rehydrating agent, an infusing agent, and a hydrosol infuser. A method of using the device is also disclosed. The method can comprise rotating the first housing portion with respect to the second housing portion to open the device, placing the device within a bag or container containing the plant or plant-derived matter, and sealing the bag or container containing the plant or plant-derived matter and the device.

Abstract: The present invention relates to the provision of genetically modified fungal cells, such as yeast cells with an improved ability for producing different fatty acids and specifically fatty acid ethyl esters (FAEE), the main components of biodiesel. An increased in fatty acid production, and hence in FAEE, is obtained in the first place by expressing different heterologous polypeptides in combination with the down-regulation, attenuation, deletion or over-expression of specially selected genes, wherein said genes encode enzymes involved in the fatty acids synthesizing pathway, fatty acid consuming pathways, carbohydrate biosynthesis pathways or enzyme acting as wax ester transporters or a combination thereof. The methods and products of the invention would allow large-scale production of FAEE with carbohydrates as the only externally-supplied substrate.

Abstract: The apparatus for dispensing cosmetics has a bottle portion configured to hold the cosmetics product, a wiper structure at an open end of the bottle portion; and a closure portion.

Abstract: A novel hot-melt adhesive and a preparation method thereof are disclosed, and in particular a hot-melt adhesive for bonding aluminum, stainless steel or other metal materials and PVC plastics is disclosed. The specific nylon-type copolyamide is firstly prepared by designing specific raw materials and percentage thereof, and in combination with favorable bonding properties of the nylon-type copolyamide for metals and favorable bonding characteristics of the perchloroethylene resin for PVC, a double screw extruder is utilized to perform sufficient melt blending on the nylon-type copolyamide and the perchloroethylene resin under the synergistic actions of related aids, so that the obtained novel hot-melt adhesive has favorable bonding properties for both metals and PVC.

Abstract: An illustrative example level detector for a hot melt system includes a scale having a load cell and a controller having an indicator configured to alert an operator when a weight detected by the load cell has decreased by a user-selected maximum allowable amount.

Abstract: Pharmaceutical compositions and methods for inducing conscious sedation using such compositions are described, the compositions comprising a benzodiazepine-based compound, a NMDA antagonist, and optionally a ?-blocker, antiemetic, an NSAID, and/or an antihistamine medication. Methods for fabricating the compositions and using them for anesthesiological applications are also described.

Abstract: A novel copolyester hot-melt adhesive and a preparation method thereof are disclosed. The preparation method mainly includes the following steps: selecting raw materials according to preset ratios, wherein the raw materials include: bisphenol A, maleic acid, terephthalic acid, another dibasic acid, 1,4-butanediol, another dibasic alcohol, catalysts and a stabilizer; producing a prepolymer under negative pressure in a low-temperature section, completing an esterification process under normal pressure in the low-temperature section, and completing a polycondensation step under negative pressure in a high-temperature section, thereby finally preparing the novel copolyester hot-melt adhesive product.

Abstract: A composite hot-melt adhesive mesh film and preparation process thereof, in particular, a composite hot-melt adhesive mesh film and preparation process thereof for bonding metal and non-polar material are disclosed. The mesh film is compounded of a polar polyamide hot-melt adhesive and a non-polar polyolefin hot-melt adhesive mesh film containing a compatibilizer. The mesh film has a high adhesive strength and a durable and stable adhesion, and is especially suitable for bonding stainless steel, aluminum, copper or other metal materials and polyethylene, polypropylene or other non-polar polymers. Additionally, the preparation process is completed in one set of production process from raw material pretreatment to the final preparation of the hot melt adhesive mesh film product, thereby greatly reducing production failures, and providing high production efficiency and low costs.

Abstract: Pharmaceutical compositions and methods for inducing conscious sedation using such compositions are described, the compositions comprising a benzodiazepine-based compound, a NMDA antagonist, and optionally a ?-blocker, antiemetic, an NSAID, and/or an antihistamine medication. Methods for fabricating the compositions and using them for anesthesiological applications are also described.

Abstract: A method for preparation of a high-viscosity polyester hot-melt adhesive with a partially sensitive viscosity-temperature property is disclosed, including the steps of: i) subjecting terephthalic acid, isophthalic acid, dodecanedioic acid, adipic acid, butanediol, dipropylene glycol and hexanediol to an esterification reaction in the presence of tetrabutyl titanate serving as a catalyst; and ii) adding an antioxidant to a product resulting from step i) to conduct a polycondensation reaction under a reduced pressure so as to obtain the high-viscosity polyester hot-melt adhesive which has a low melting point of 130° C.-135° C. and a partially sensitive viscosity-temperature property.

Abstract: The apparatus has a closure portion and a bottle portion; the closure portion holds the eyeliner mechanism, which comprises: a sliding sleeve, a compression spring, a stem and an applicator tip; the second end of the stem has a cap or end portion; the closure portion has a body or housing that holds the eyeliner mechanism; the sliding sleeve, compression spring and the stem allow the eyeliner mechanism to have a retracted and an extended position; the sliding sleeve and the stem can have a receptacle or groove that engages the compression spring.

Abstract: The invention relates to a melter, comprising a block (2) having a detachable shell (6), in which there is housed a melting chamber (3) provided with an upper opening that is closed with a hinged and detachable lid (11), the chamber (3) being arranged on lower supports (7), with the freedom to expand upwards, the opening of said chamber (3) incorporating a gasket (8) having an upwardly inclined flexible lip in the outer part on which the shell (6) rests, establishing sealed closure with respect to the chamber (3), whereas on the gasket (8) there is arranged a frame (9) having an upward vertical flange, with respect to which the lid (11) that closes on the gasket (8) is assembled, such that when the chamber (3) expands due to the temperature, the flexible lip allows the expansion maintaining leak-tightness.

Abstract: According to some aspects, a system for producing a target molten metal composition is provided. The system includes a sorting device that sorts input pieces of metal based on a control signal. Sorted pieces of metal are melted in a furnace, and a sensor measures the composition of molten metal in the furnace and in response generates a control signal that is sent to the sorting device.

Abstract: A method for preparation of a high-viscosity polyester hot-melt adhesive with a partially sensitive viscosity-temperature property is disclosed, including the steps of: i) subjecting terephthalic acid, isophthalic acid, dodecanedioic acid, adipic acid, butanediol, dipropylene glycol and hexanediol to an esterification reaction in the presence of tetrabutyl titanate serving as a catalyst; and ii) adding an antioxidant to a product resulting from step i) to conduct a polycondensation reaction under a reduced pressure so as to obtain the high-viscosity polyester hot-melt adhesive which has a low melting point of 130° C.-135° C. and a partially sensitive viscosity-temperature property.

Abstract: A catering box with active climate control is configured to transport “delicate” foods, such as grilled cheese sandwiches, hot dogs, and hamburgers, without inducing substantial sogginess in the bread of those food items. The catering box includes a heat mass configured to retain heat generated by a hot plate and to then radiate that heat, during transport, after the hot plate has been disconnected from a power source. In addition, the catering box includes an exhaust fan that actively controls internal specific humidity levels in order to prevent moisture from settling within the bread of stored food items. A microcontroller within the catering box monitors temperature and absolute humidity levels, computes the current specific humidity level, and then selectively engages or disengages the exhaust fan in response. With his approach, the catering box may limit the degree to which humidity settles within the bread of delicate food items stored within.

Abstract: The invention relates to a melter, comprising a block (2) having a detachable shell (6), in which there is housed a melting chamber (3) provided with an upper opening that is closed with a hinged and detachable lid (11), the chamber (3) being arranged on lower supports (7), with the freedom to expand upwards, the opening of said chamber (3) incorporating a gasket (8) having an upwardly inclined flexible lip in the outer part on which the shell (6) rests, establishing sealed closure with respect to the chamber (3), whereas on the gasket (8) there is arranged a frame (9) having an upward vertical flange, with respect to which the lid (11) that closes on the gasket (8) is assembled, such that when the chamber (3) expands due to the temperature, the flexible lip allows the expansion maintaining leak-tightness.

Abstract: A polyester/glyoxalated polyvinyl alcohol semi-interpenetrating polymer network hot-melt adhesive and preparation method therefore, mainly includes the steps of: 1) transesterification of certain amounts of dimethyl terephthalate and another dibasic ester with 1,4-butanediol and other diols in the presence of an organotin catalyst under a nitrogen atmosphere in a reactor, completed upon the amount of distillation of a monohydric alcohol byproduct reaching greater than 95% of the theoretical amount; 2) after the temperature is maintained for a period of time, adding in a stabilizer and a polycondensation catalyst and incrementally increasing the temperature to trigger a polycondensation reaction under a reduced pressure to produce particles of a copolymer, and freezing and pulverizing the copolymer particles to produce a powder of a copolyester; 3) uniformly blending a polyvinyl alcohol/glyoxal mixture with the powder produced in step 2) at ambient temperature to produce the target product.