Abstract: A method and apparatus for photon counting are disclosed. In an implementation, the present disclosure provides a dynamic-range photon-counting spectrometric sensor for low signal detection embedded in large parasitic background light signal. Rather than using a known forward illuminated imager approach of counting photons directly, embodiments of the present disclosure use a backward illuminated imager approach to generate a burst of electrons based on the photons, and perform photon detection by counting the generated burst of electrons using the plurality of CMOS chip pixels. An electronic circuit, in communication with the CMOS chip pixels, includes a fast clock enabling discrimination between electrons in time. The electronic circuit can be built on the face of a semiconductor wafer on which the CMOS chip pixels are provided.

Abstract: Systems and methods for use in training crewmembers in the cargo compartment in detecting and identifying visual cues related to potential threats to aircraft and to ground based search and rescue circumstances. A visual display displays a scene generated by a visual scene generator apparatus. A vision limiting device, such as an actual door from an aircraft, equipped with a window is placed between the trainee and the visual display and the trainee can only see a limited amount of the visual display through the door's window. The limited view of the scene afforded the trainee will force the trainee to move around at various angles to see more of the scene and will also provide a frame of reference for making spatiotemporal judgments regarding the relationships between the trainee, the trainee's aircraft, and objects external to the aircraft.

Abstract: Methods and systems for presenting document search results to a user. A user enters search terms to be matched with indicators mentioned in documents from a specific corpus of documents. The search results, which are the documents with indicators or content that match the search terms, are provided to the user using a user interface. Each document in the search results are represented by a marker on a map in the user interface. Other indicators which appear with the searched for indicators in the documents are also mapped to the user interface. Documents with similar indicators in their content are clustered together in the map and the markers which represent them are color coded to differentiate them from markers belonging to other clusters.

Abstract: A system for determining the detectability of a fleet of vehicles by a listener at a target site. The system receives as input at least the number of vehicles, a selection of a noise signature for each vehicle, and a distance to the target. The system may then estimate noise pressure level for the fleet along the estimated distance from the given location to the target site based on the noise signature associated with each vehicle and display a graph showing the noise pressure level vs. distance from the given location to the target site. In an embodiment, the system may estimate the background noise level at the target site and subtract this from the noise pressure level of the fleet at the target site to determine an expected noise level above background noise at the target site.

Abstract: A multibranched N-doped carbon nanotube (CNT) and the process of production are described. The CNT includes a first-stage stalk having a direction comprising a first-stage base, and a first-stage top opposite to and attached with the first-stage base, at least two second-stage bundles, each of which comprises a second-stage base attached to the first-stage top, and second-stage top opposite to and attached with the second-stage base, and wherein the second-stage bundles branch from the first-stage stalk in substantially the direction of the first stage stalk, and a plurality of third-stage nanotubes each of which comprises a third-stage base attached to the second-stage top, a third-stage top opposite to and attached with the third-stage base, and wherein the plurality of third-stage nanotubes branch from the second-stage bundles.

Abstract: A man portable device for detecting the presence of hazardous material includes a pulsed or time-modulated light source and an objective scannable across the surface of a sample for projecting light from the light source onto a succession of spots on the surface of the sample. A spectrometer performs a spectral analysis of the induced fluorescence to create a first dataset defining a first vector as a function of wavelength. A time domain detector for measuring the time decay of the induced fluorescence collected simultaneously creates a second dataset defining a second vector as a function of time. A computer identifies hazardous material by performing independent multivariate analysis on the first and second vectors as the objective is scanned across the sample surface based on fluorescent signal models for hazardous materials in the spectral and time domains.

Abstract: A man portable device for detecting the presence of hazardous material includes a pulsed or time-modulated light source and an objective scannable across the surface of a sample for projecting light from the light source onto a succession of spots on the surface of the sample. A spectrometer performs a spectral analysis of the induced fluorescence to create a first dataset defining a first vector as a function of wavelength. A time domain detector for measuring the time decay of the induced fluorescence collected simultaneously creates a second dataset defining a second vector as a function of time. A computer identifies hazardous material by performing independent multivariate analysis on the first and second vectors as the objective is scanned across the sample surface based on fluorescent signal models for hazardous materials in the spectral and time domains.

Abstract: The present invention relates to anti-ricin antibodies and uses thereof. More specifically, the invention relates to anti-ricin antibodies and fragments thereof as well as their use in therapy or prophylaxis.

Abstract: Systems and devices for protecting a user's head and for integrating accessories with a head protection system. The head protection system uses a rigid shell worn on the user's head and the rigid shell has a power/data bus located inside a preconfigured channel inside a halo housing attached to the shell. This power/data bus is accessible to peripherals using distinct connection points both inside and outside the shell. Removable protection accessories are also provided and attachable to the shell using an attachment subsystem located on the inside edge of the shell. The attachment subsystem has a number of recesses which mate with tabs on the removable protection accessories. Once attached to the shell, the removable protection accessories are lockable into place using a suitable locking mechanism. A nape protection attachment, a mandibular guard attachment, a visor attachment, and other protection accessories may be attached to the shell.

Abstract: Disclosed herein is a compound having Formula I: or a salt thereof, in which R1, R2 and R3 are as defined herein. Also disclosed are processes to prepare compounds of Formula I and use of compounds of Formula I to prepare stable glassy phases.

Abstract: There is described a pulsed eddy current sensor for measurement of a lift-off distance over a surface of a metallic substrate (a metallic surface). The pulsed eddy current sensor comprises: a primary excitation coil to which are applied voltage pulses for generating primary magnetic fields, wherein an interaction of the primary magnetic fields with the metallic substrate produces secondary magnetic fields; and secondary pick-up probes, each of the secondary pick-up probes located at a different vertical distance from the metallic surface, the secondary pick-up probes used for measuring the primary and secondary magnetic fields and for producing a differential signal that is representative of the lift-off distance.

Abstract: A submarine homing system includes an acoustic emitter configured to emit an acoustic signal comprising at least two narrow-band tones, each narrow-band tone having a respective predetermined center frequency. An acoustic receiver is configured to receive the acoustic signal from the acoustic emitter, and produce one or more receiver signals. A processor is operatively connected to the acoustic receiver. The processor is configured to process the receiver signals to calculate a direction between the acoustic receiver and the acoustic emitter.

Abstract: Poly ICLC or liposome-encapsulated Poly ICLC (LE Poly ICLC) in combination with antisense oligonucleotides (AS) act synergistically in post-exposure prophylaxis or therapy of influenza infections, especially H5N1 virus infections.

Abstract: The present invention provides a system and method for relative localization that provides an orientation signal and a position signal between at least two vehicles. The present invention also provides for vehicle formation, such that there is a leading vehicle and a follower vehicle that maintain a specific formation relative to one another. The orientation, relative position and identity signals are utilized to control that formation. Each vehicle has at least three ultrasonic sensors, at least one ultrasonic source and an optional pair of FM receiver/transmitter. By installing several acoustic sensors whose relative position are known and by measuring the difference in the time of arrival of the same signal from the various sensors on the same vehicle, the difference in time can be converted into a difference of distance and then into relative position of the sensors from the source based on the Time Difference of Arrival (TDOA).

Abstract: Methods and systems for presenting document search results to a user. A user enters search terms to be matched with indicators mentioned in documents from a specific corpus of documents. The search results, which are the documents with indicators or content that match the search terms, are provided to the user using a user interface. Each document in the search results are represented by a marker on a map in the user interface. Other indicators which appear with the searched for indicators in the documents are also mapped to the user interface. Documents with similar indicators in their content are clustered together in the map and the markers which represent them are color coded to differentiate them from markers belonging to other clusters.

Abstract: A submarine homing system includes an acoustic emitter configured to emit an acoustic signal comprising at least two narrow-band tones, each narrow-band tone having a respective predetermined center frequency. An acoustic receiver is configured to receive the acoustic signal from the acoustic emitter, and produce one or more receiver signals. A processor is operatively connected to the acoustic receiver. The processor is configured to process the receiver signals to calculate a direction between the acoustic receiver and the acoustic emitter.

Abstract: Systems and methods related to the detection of incoming wireless signals. An antenna array is synthesized by having a single antenna, coupled to a receiver, spatially translated along an arbitrary trajectory. As the antenna is being spatially translated, a data processing means samples the incoming signal based on a clock signal provided by a system clock. By sampling the incoming signal at different times at different spatial locations on the arbitrary trajectory, the system acts as a synthetic antenna array. The different samplings of the incoming signal at different times and positions provide signal diversity gain as well as different readings which can be used to detect an incoming signal. The invention is applicable to detecting a wireless communications signal or a GNSS signal under various conditions. The system may include at least one sensor which can provide data for use in calculating data related to the arbitrary trajectory.

Abstract: Isolated and/or recombinant adhesin polypeptides from Burkholderia pseudomallei are provided, which are used as vaccines. Genetic constructs comprising nucleic acid sequences encoding such polypeptides are also provided. Vectors comprising such constructs have been prepared and used for transforming host cells for producing the polypeptides of the invention. Antibodies to such polypeptides are also provided. Such antibodies can be used to detect the presence of B. pseudomallei or B. mallei and in methods of treating or preventing Burkholderia infection.

Abstract: This invention addresses how to rapidly prevent alphavirus-induced encephalitides before and after exposure to alphaviruses. The invention discloses a single dose administration of two types of recombinant viral vectors: one expressing interferon and another expressing the structural proteins of alphaviruses or a single dose administration of the recombinant viral vector co-expressing both interferon and the structural proteins of alphaviruses. This invention can be used to prevent humans from alphavirus-induced encephalitides in the event of a bioterrorism attack or biowarfare in which alphaviruses such as Venezuelan (VEEV), eastern (EEEV) and western (WEEV) equine encephalitis viruses are deliberately released to humans, a natural outbreak of alphaviruses, and an accidental exposure to alphaviruses in laboratory.

Abstract: Low molecular weight serum components (less than 10,000 m.w.), in vaccinated animals and a human subject who has been exposed to a threat agent inadvertently, bound to purified O-polysaccharide (OPS, a polymer of formamido-mannose) and a candidate of a threat agent, such as Brucella suis 145 vaccine is disclosed. These components formed a loose reversible precipitin with OPS in a high-salt borate-buffered agarose gel and bound to the candidate vaccine as observed by capillary electrophoresis. By using modified capillary electrophoresis, the invention also discloses the presence of two larger serum components, one similar in size to that of serum albumin and one resembles that of mannan-binding lectin, that bound to the vaccine. An indirect method for identifying vaccination is the presence of antibodies against Brucella-OPS-antibodies. ELISA, capillary electrophoresis and animal challenge studies showed that as high as 30% of the control animals did not require vaccination.