Patents Assigned to The National Centre for Biological Sciences, Tata Institute of Fundamental Research
  • Methods and compositions for determining pH
    Patent number: 11136618
    Abstract: Described herein are nucleic acid molecules and complexes useful as i-switch pH reporters that have increased sensitivities as a pH reporter and have alternate pH reporting capacity ranges. Aspects of the disclosure relate to a method for determining pH comprising providing a nucleic acid complex comprising: a first single-stranded nucleic acid molecule comprising the sequence CnXCnYCnZCn (SEQ ID NO.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: October 5, 2021
    Assignees: The University of Chicago, The National Centre for Biological Sciences, Tata Institute of Fundamental Research
    Inventors: Yamuna Krishnan, Saheli Halder