Patents Assigned to THE NATIONAL INSTITUTE FOR BIOTECHNOLGY IN THE NEGEV LTD. - Justia Patents Search

Patents Assigned to THE NATIONAL INSTITUTE FOR BIOTECHNOLGY IN THE NEGEV LTD.

Piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction

Patent number: 10787423

Abstract: Provided herein piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction. Also provided methods of treatment of diseases associated with said processes, e.g. Alzheimer's and Parkinson's diseases.

Type: Grant

Filed: November 4, 2019

Date of Patent: September 29, 2020

Assignee: THE NATIONAL INSTITUTE FOR BIOTECHNOLGY IN THE NEGEV LTD.

Inventors: Varda Shoshan-Barmatz, Arie Lev Gruzman