Abstract: The invention provides a vaccine comprising secreted protein derived from Mycobacterium avium subsp paratuberculosis (M. ptb) substantially free of whole organisms of that species either dead or alive. The secreted protein may be obtained from a culture of M. ptb with the microorganisms being removed by centrifugation and subsequent filtration. The vaccine may be used for vaccination against Johne's disease.
Type:
Grant
Filed:
May 13, 2008
Date of Patent:
July 20, 2010
Assignees:
Massey University, The New Zealand Meat Board, Wool Production Technologies Ltd.
Inventors:
Alan Murray, Christine DuPont, Jeremy Lawrence Rae
Abstract: The invention provides a vaccine comprising secreted protein derived from Mycobacterium avium subsp paratuberculosis (M. ptb) substantially free of whole organisms of that species either dead or alive. The secreted protein may be obtained from a culture of M. ptb with the microorganisms being removed by centrifugation and subsequent filtration. The vaccine may be used for vaccination against Johne's disease.
Type:
Grant
Filed:
August 7, 2002
Date of Patent:
June 17, 2008
Assignees:
Massey University, The New Zealand Meat Board, Wool Production Technologies Ltd
Inventors:
Alan Murray, Christine Dupont, Jeremy Lawrence Rae