Abstract: Tocopheryl succinate derivatives according to formula I: are described. These compounds increase the activity of protein phosphatase 2A, can be included in pharmaceutical compositions, and can be used for the treatment of androgen receptor-dependent cancers such as prostate cancer.
Type:
Application
Filed:
April 13, 2010
Publication date:
October 21, 2010
Applicant:
THE OHIO SATE UNIVERSITY RESEARCH FOUNDATION
Inventors:
Ching-Shih Chen, Dasheng Wang, Samuel K. Kulp