Patents Assigned to The Plant Cell Research Institute, Inc.
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Patent number: 4933286Abstract: An isoenzyme from tomato, acid phosphatase-1 isoenzyme (Apase-1.sup.1), has ben purified to homogeneity and is subjected to amino acid sequencing and used to prepare anti-Apase-1 antibodies. The amino acid sequence permits design of probes to recover Apase-1.sup.1 -encoding cDNA; the antibodies are also useful for this purpose. The cDNA is useful to recover the genomic DNA encoding Apase-1.sup.1, which can then be used in walking or jumping techniques to recover the genomic DNA which confers nematode resistance, since this DNA resides immediately adjacent to the Apase-1.sup.1 gene on chromosome 6 of Lycopersicon esculentum.Type: GrantFiled: March 30, 1987Date of Patent: June 12, 1990Assignee: Plant Cell Research Institute, Inc.Inventors: Elizabeth M. Paul, Valerie M. Williamson, Jack L. Erion, Candace G. Poutre
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Patent number: 4876277Abstract: Substituted olefinic (allyl) benzene compounds which exhibit important antimicrobial (antibacterial and antifungal) activity, compositions and methods of delivery against pathovars and pathogens, and methods of synthesis from commonly available reactants. The antifungal composition active ingredient is one or more 4,5-substituted 2,3-alkylidenedioxy-1-olefinic benzenes of the formula: ##STR1## where R.sub.1 and R.sub.2 may be the same or different, and are selected from OH, and C.sub.1 -C.sub.5 alkoxy (--OR) or thioalkyl (--SR) groups. R.sub.3 and R.sub.4 are selected from H and C.sub.1 -C.sub.5 alkyl, alkenyl and alkynyl groups, and R.sub.5 is selected from C.sub.3 -C.sub.7 alkyl, alkenyl and alkynyl groups. The preferred compounds are 4,5-substituted-2,3-methylenedioxy-1-allyl benzenes. Where R.sub.1 =OCH.sub.3, R.sub.2 =OH, R.sub.3 and R.sub.4 =H and R.sub.5 =allyl (2',3' propenyl) the compound may be called nor methyl-pseudo-dillapiole. Where R.sub.1 =R.sub.2 =OCH.sub.3, R.sub.3 and R.sub.Type: GrantFiled: May 29, 1987Date of Patent: October 24, 1989Assignee: Plant Cell Research Institute, Inc.Inventors: Basil A. Burke, Muraleedharan G. Nair
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Patent number: 4751292Abstract: The present invention comprises novel adamantyl purine derivatives, in which the purine ring is substituted at the 6-position with a moiety incorporating an adamantane ring system. The purine may also be substituted at the 9-position with a carbohydrate, to give a nucleoside analog, or may be unsubstituted at that position.The substituent at the 6-position contains an adamantane ring system, either substituted or unsubstituted, in which a linker connects a carbon atom in the adamantane ring system with the 6-carbon of the purine ring. This linker consists of a combination of a heteroatom such as N, O or S, which is directly connected to the purine, and a short (five or less) atom chain, consisting either of carbon or other atoms such as N, O or S, with or without additional pendant moieties, which is connected either to the secondary or tertiary carbon of the adamantane ring system. The adamantane ring system itself may be unsubstituted, or substituted with a wide variety of non-ionic groups.Type: GrantFiled: July 2, 1985Date of Patent: June 14, 1988Assignee: The Plant Cell Research Institute, Inc.Inventor: Juan E. Fox
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Patent number: 4745186Abstract: The present invention comprises a new class of 2,3,4-tri-O-acylhexoses and mixtures thereof. Members of the new class of compounds are comprised of a hexose sugar having fatty acids attached at the 2, 3 and 4 positions of the hexose moiety. The fatty acids can be saturated or unsaturated, and can have a relative molecular size of up to C.sub.30. When at least one of the acylating fatty acid groups on the hexose molecule contains more than 7 carbons, the resulting 2,3,4-tri-O-acylhexoses (or mixtures thereof) have a non-bitter taste. On the other hand, when none of the acylating fatty acids have more than 7 carbons, the resulting 2,3,4-tri-O-acylhexoses (and mixtures that contain them) are bitter when tasted.The new 2,3,4-tri-O-acylhexoses can be synthesized using known chemical methods. Alternatively, the new compounds, and especially mixtures thereof, are obtained as the result of selective extraction and purification of the epicuticular exudate from Lycopersicon pennellii plant parts.Type: GrantFiled: February 10, 1986Date of Patent: May 17, 1988Assignee: Plant Cell Research Institute, Inc.Inventors: John B. Mudd, Basil A. Burke, Jon F. Fobes, Muraleedharan G. Nair