Abstract: Disclosed is a new composition of matter, substantially enantiomerically pure (1R,6S)-2-Azabicyclo-[4.3.0]nonane-8,8-diphosphonic acid, methods of preparing this new composition of matter, a pharmaceutical composition comprising the new composition, and administration of the composition in methods of treating bone disorders such as osteoporosis, osteolytic bone metastasis, rheumatoid arthritis and osteoarthritis.
Type:
Application
Filed:
December 11, 2007
Publication date:
March 12, 2009
Applicant:
The Procter & Gamble Company and University of Rochester
Inventors:
Frank Hallock Ebetino, Robert Kenneth Boeckman, JR., Xinyi Song