Abstract: A device (100) for measuring ocular microtremor (OMT) of a patient's eye, comprises a light source (10) for illuminating a target area of the eye with a light beam. The device also comprises a detector (20) arranged to detect scattered light from the interaction of the light beam with the target area of the eye. The device further comprises a focusing lens (30) arranged to collect the scattered light for the detector, and a port in a wall of the device through which the light beam can exit the device and/or through which the scattered light can enter the device. The device is configured to stabilise and/or support the device on or against a patients head. A method of measuring microtremor of an eye is also provided.
Type:
Application
Filed:
August 29, 2019
Publication date:
April 28, 2022
Applicant:
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOL
Abstract: A heart valve therapeutic device (1) comprises a coaptation assist valve (20) comprising a conduit (2) with an outer surface (3) for coaption with the native leaflets, and a prosthetic flow valve (5) mounted within the conduit (2) to allow one-way flow through the conduit (2). Support for the coaptation assist valve (20) is provided by a support (10) for positioning the conduit (2) across the native leaflets, and connectors (15) attaching the conduit (2) to the support (10).
Type:
Application
Filed:
December 21, 2021
Publication date:
April 14, 2022
Applicant:
The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Hol
Inventors:
Paul Heneghan, Bruce Murphy, Lucy O'Keeffe, Martin Quinn, Conor Quinn
Abstract: A heart valve therapeutic device (1) comprises a coaptation assist valve (20) comprising a conduit (2) with an outer surface (3) for coaption with the native leaflets, and a prosthetic flow valve (5) mounted within the conduit (2) to allow one-way flow through the conduit (2). Support for the coaptation assist valve (20) is provided by a support (10) for positioning the conduit (2) across the native leaflets, and connectors (15) attaching the conduit (2) to the support (10).
Type:
Application
Filed:
July 30, 2020
Publication date:
November 12, 2020
Applicant:
The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Hol
Inventors:
Paul HENEGHAN, Bruce MURPHY, Lucy O'KEEFFE, Martin QUINN, Conor QUINN
Abstract: The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.
Type:
Application
Filed:
August 7, 2019
Publication date:
November 28, 2019
Applicants:
THE UNIVERSITY OF QUEENSLAND, THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOL
Inventors:
Luke O'NEILL, Rebecca COLL, Matthew COOPER, Avril ROBERTSON, Kate SCHRODER
Abstract: (E)-2-(2-Quinolin-2-yl-propenyl)-phenol, 2-Quinolin-2-yl-ylethynyl-phenol and salts thereof are useful as medicaments, especially for treatment of an angiogenesis-related disease or disorder.
Type:
Application
Filed:
June 28, 2016
Publication date:
February 23, 2017
Applicants:
University College Dublin National University of Ireland, Dublin, The Provost, Fellows, Foundation Scholars, and the other members of Board, of the College of the Hol
Inventors:
Breandan Noel KENNEDY, Alison REYNOLDS, Claire KILTY, Jacintha O'SULLIVAN, Andrew Douglas BAXTER