Patents Assigned to The Queen Elizabeth Hospital Research Foundation Inc.
  • Patent number: 7722866
    Abstract: The present invention provides methods for inhibiting cancerous growth of a cell using an antibody or an antigen-binding portion thereof which binds to an epitope of EphB4 polypeptide. Purified antibodies of EphB4 are also provided. The invention also provides methods for preventing or treating cancer. The invention also relates to methods of identifying agents that can inhibit cancerous growth of a cell.
    Type: Grant
    Filed: September 16, 2003
    Date of Patent: May 25, 2010
    Assignee: The Queen Elizabeth Hospital Research Foundation, Inc.
    Inventor: Sally-Anne Stephenson
  • Patent number: 7455970
    Abstract: The present invention relates to a method of identifying a subject predisposed to ischemic stroke. The method includes the step of identifying a mutation in the subject that reduces the release rate of tissue plasminogen activator.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: November 25, 2008
    Assignees: The Queen Elizabeth Hospital Research Foundation Inc., Adelaide Research & Innovation Pty Ltd
    Inventors: Jim Jannes, Monica Anne Hamilton-Bruce, Simon Koblar
  • Publication number: 20080241824
    Abstract: The present invention relates to a method of identifying a subject predisposed to lacunar stroke. The method includes the step of identifying in the subject the presence of a thymine to cytosine mutation at position -107 in both alleles of the paraoxonase 1 locus.
    Type: Application
    Filed: February 18, 2005
    Publication date: October 2, 2008
    Applicants: THE QUEEN ELIZABETH HOSPITAL RESEARCH FOUNDATION INC., Adelaide Research & Innovation Pty Ltd.
    Inventors: Jim Jannes, Monica Anne Hamilton-Bruce, Simon Koblar
  • Publication number: 20070105110
    Abstract: The present invention relates to a method of identifying a subject predisposed to ischemic stroke. The method includes the step of identifying a mutation in the subject that reduces the release rate of tissue plasminogen activator.
    Type: Application
    Filed: July 2, 2004
    Publication date: May 10, 2007
    Applicants: THE QUEEN ELIZABETH HOSPITAL RESEARCH FOUNDATION INC., Adelaide Research & Innovation Pty Ltd.
    Inventors: Jim Jannes, Monica Hamilton-Bruce, Simon Koblar
  • Publication number: 20060134118
    Abstract: The present invention provides methods for inhibiting cancerous growth of a cell using an antibody or an antigen-binding portion thereof which binds to an epitope of EphB4 polypeptide. Purified antibodies of EphB4 are also provided. The invention also provides methods for preventing or treating cancer. The invention also relates to methods of identifying agents that can inhibit cancerous growth of a cell.
    Type: Application
    Filed: September 16, 2003
    Publication date: June 22, 2006
    Applicant: The Queen Elizabeth Hospital Research Foundation Inc.
    Inventor: Sally-Anne Stephenson
  • Publication number: 20050143463
    Abstract: The present invention relates to a method of inhibiting endothelial cell proliferation in a biological system, the method including the step of administering to the biological system an effective amount of an alkyl-substituted fatty acid, wherein the alkyl-substituted fatty acid is capable of inhibiting endothelial cell proliferation.
    Type: Application
    Filed: November 3, 2004
    Publication date: June 30, 2005
    Applicant: THE QUEEN ELIZABETH HOSPITAL RESEARCH FOUNDATION INC.
    Inventor: Ravi Krishnan