Patents Assigned to The Radiochemical Centre Limited
  • Calibration source
    Patent number: 4033884
    Abstract: A Flood Source for calibration of gamma-cameras comprises the nuclide Tellurium-123m in a solution contained uniformly within a liquid-retaining plastics sheet of uniform thickness. The plastics sheet may be enclosed in a protective metallic casing.
    Type: Grant
    Filed: January 24, 1975
    Date of Patent: July 5, 1977
    Assignee: The Radiochemical Centre Limited
    Inventors: Edgar Adolf Lorch, Keith Ernest Fletcher, David Page
  • Saturation analysis
    Patent number: 4030886
    Abstract: The invention provides a method and a kit for the saturation analysis of a steroid characterized by the use of a selenium-75 labelled version of the steroid to be assayed. Selenium-75 derivatives of steroids are quite simple to prepare and have practical advantages over other radioactively labelled steroids. Lists of derivatives and examples of competitive radio-assays are given.
    Type: Grant
    Filed: December 5, 1974
    Date of Patent: June 21, 1977
    Assignee: The Radiochemical Centre Limited
    Inventors: Russell James Bayly, Virginia Edith May Chambers, Reginald Monks
  • Labelled derivatives of steroids
    Patent number: 4029880
    Abstract: Radio-iodine derivatives of digoxin and digitoxin are provided having the formula IV, whereR is H or lower alkyln is 1, 2 or 3Y is H or carboxylm is 0 to 5, andQ is a phenolic or imidazole ring,To which radio-iodine atoms are attached. Novel intermediates in the preparation of the radio-iodine derivative are described. The derivatives are useful for the radioimmunoassay of digoxin and digitoxin.
    Type: Grant
    Filed: June 19, 1975
    Date of Patent: June 14, 1977
    Assignee: The Radiochemical Centre Limited
    Inventors: Keith Charles Tovey, John William Addison Findlay
  • Organ visualization
    Patent number: 4024234
    Abstract: Novel selenium-75 derivatives of cholesterol have the formula ##STR1## (I) where X is hydrogen or acyl, Y is alkyl and n is 0 or 1. They are useful for visualizing the adrenal glands of mammals.
    Type: Grant
    Filed: February 19, 1975
    Date of Patent: May 17, 1977
    Assignee: The Radiochemical Centre Limited
    Inventors: Reginald Monks, Anthony Leonard Mark Riley, Gavin Murray Cree
  • Immunoassays employing a colored second antibody
    Patent number: 3985867
    Abstract: In some radioimmunoassays, the antigen competes with labelled antigen for reaction with a first antibody and the antigen-antibody complex is precipitated by reaction with an aqueous solution of a second antibody to the first antibody. The invention consists in using an artificially colored second antibody, so that the precipitate is easily visible to the naked eye.
    Type: Grant
    Filed: December 26, 1974
    Date of Patent: October 12, 1976
    Assignee: The Radiochemical Centre Limited
    Inventor: Martin Ralphs Redshaw
  • Technetium-99m-tin-monofluorophosphate complex
    Patent number: 3984531
    Abstract: Aqueous fluids for skeletal imaging comprise technetium-99m present as a bone-seeking technetium-99m/tin/phosphate complex, are prepared using a monofluorophosphate and stannous fluoride or chloride, the molar proportion of monofluorophosphate to stannous ion being from 30:1 to 500:1, to react with pertechnetate. Kits for skeletal imaging comprise mixture of monofluorophosphate with stannous ion for reaction with pertechnetate.
    Type: Grant
    Filed: February 15, 1974
    Date of Patent: October 5, 1976
    Assignee: The Radiochemical Centre Limited
    Inventor: John Barry Laidler
  • Composition comprising radioactive labeled-fibrinogen and albumin
    Patent number: 3933996
    Abstract: The stability of fibrinogen is improved by mixing it with albumin, preferably at least 5 parts by weight of albumin per part by weight of fibrinogen. By this invention, iodinated (.sup.125 I) human fibrinogen can be stabilised with human serum albumin for use in the diagnosis of thrombi.
    Type: Grant
    Filed: June 19, 1973
    Date of Patent: January 20, 1976
    Assignee: The Radiochemical Centre Limited
    Inventors: John Cecil Charlton, David Lawrence Gravett