Abstract: The present invention relates to a process for the preparation of hydrogen peroxide from oxygen or oxygen-delivering substances and hydrogen or hydrogen-delivering substances in the presence of at least one catalyst containing a metal-organic framework material, wherein said framework material comprises pores and a metal ion and an at least bidentate organic compound, said bidentate organic compound being coordinately bound to the metal ion. The invention further relates to a novel material consisting of said metal organic framework material wherein the material is brought in contact with at least one additional metal.

Abstract: The movement and mixing of microdroplets through microchannels is described employing microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and radiation detectors. Microdroplets are metered into defined volumes and are subsequently incorporated into a variety of biological assays. Electronic components are fabricated on the same substrate material, allowing sensors and controlling circuitry to be incorporated in the same device.

Abstract: The invention relates generally to compositions of and methods for obtaining and using a polypeptide other than BCL-2 that affects programmed vertebrate cell death. The invention relates as well to polynucleotides encoding those polypeptides, recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant polypeptides. The invention further provides methods for using the isolated, recombinant polypeptides in assays designed to select and improve substances capable of altering programmed cell death for use in diagnostic, drug design and therapeutic applications.

Abstract: Compositions and methods are described for nucleic acid formulation for gene delivery. A new class of low molecular weight condensing agents, namely aromatic amino acid—containing peptides, are described for use in receptor-mediated and nonreceptor-mediated gene delivery, both in vivo and in vitro.

Abstract: An improvement over the standard Sanger Method for nucleic acid sequencing is described. The novel method does not require denaturation of double-stranded template; rather, sequencing can be carried out directly on the double-stranded template. Embodiments are described with and without oligonucleotide primers.

Abstract: This invention provides a means of measurement tissue pressure in muscle compartments and other regions in humans and other animals. An appropriate length, for example, 6 to 12 inches of thin plastic tubing, typically less than 3 mm outside diameters, is prepared as a working part of the tissue pressure transducer. A portion of the plastic tubing including the thin wall section such as a bubble is inserted into the muscle tissue for which pressure measurement is desired to be made. A fluid is circulated through the tubing at a constant flow rate. When the internal pressure of the tubing is greater than the external pressure, the bubble expands and there is no increase in the flow resistance of the system. When the pressure on the outside exceeds the normal system operating pressure, the thin wall section or bubble contracts, resistance to flow increases, and the system pressure increases. This increase in system pressure is directly proportional to tissue pressure.

Abstract: Hybrid-myeloma cells which produce monoclonal antibody specific to the .beta. subunit of human chorionic gonadotropin and methods of use of the monoclonal antibody.