Patents Assigned to THE REGENCTS OF THE UNIVERSITY OF CALIFORNIA
  • Novel Indications for Transforming Growth Factor-Beta Regulators
    Publication number: 20080206219
    Abstract: Methods, compounds and compositions for the modulation of TGF-? are disclosed wherein the vascular permeability in a subject is altered. The compounds can be antagonists or agonists, and can be oligonucleotides, antisense oligonucleotides, small molecules, antibodies, and the like. Compounds that modulate TGF-?, regulate TGF-? bioavailabililty, or the configuration and context of type 1 collagen can be used for the treatment or prevention of diseases caused by vascular permeability.
    Type: Application
    Filed: August 9, 2004
    Publication date: August 28, 2008
    Applicant: THE REGENCTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Lisa M. Coussens, Zena Werb