Patents Assigned to The Regents of California
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Patent number: 12063788Abstract: A thin film molecular memory is provided that satisfies criteria needed to make a molecular spintronic device, based on spin crossover complexes, competitive with silicon technology. These criteria include, device implementation, a low coercive voltage (less than 1V) and low write peak currents (on the order of 104 A/cm2), a device on/off ratio >10, thin film quality, the ability to “lock” the spin state (providing nonvolatility), the ability to isothermally “unlock” and switch the spin state with voltage, conductance change with spin state, room temperature and above room temperature operation, an on-state device resistivity less than 1 ?·cm, a device fast switching speed (less than 100 ps), device endurance (on the order of 1016 switches without degradation), and the ability of having a device with a transistor channel width of 10 nm or below.Type: GrantFiled: January 25, 2022Date of Patent: August 13, 2024Assignees: NUTECH VENTURES, GEORGIA TECH RESEARCH CORPORATION, THE TRUSTEES OF INDIANA UNIVERSITY, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Peter A. Dowben, Ruihua Cheng, Xiaoshan Xu, Alpha T. N'Diaye, Aaron Mosey, Guanhua Hao, Thilini K. Ekanayaka, Xuanyuan Jiang, Andrew J. Yost, Andrew Marshall, Azad J. Naeemi
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Publication number: 20230181607Abstract: Disclosed herein, inter alia, are methods of using thiosaccharide compounds for treating coronavirus infection.Type: ApplicationFiled: May 11, 2021Publication date: June 15, 2023Applicants: The University of the Regents of California, University College DublinInventors: John Vincent Fahy, Irina Gitlin, Wilfred Raymond, Stefan Oscarson
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Patent number: 10580591Abstract: A metal oxide anchored graphene and carbon nanotube hybrid foam can be formed via a two-step process. The method can include forming at least one graphene layer and a plurality of carbon nanotubes onto a surface of a porous metal substrate by chemical vapor deposition to form a coated porous metal substrate, and depositing a plurality of metal oxide nanostructures onto a surface of the coated porous metal substrate to form the metal oxide anchored graphene and carbon nanotube hybrid foam.Type: GrantFiled: November 5, 2013Date of Patent: March 3, 2020Assignee: THE REGENTS OF CALIFORNIA, RIVERSIDEInventors: Wei Wang, Shirui Guo, Cengiz S Ozkan, Mihrimah Ozkan
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Patent number: 7662785Abstract: This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.Type: GrantFiled: February 9, 2005Date of Patent: February 16, 2010Assignees: The Regents of California, Lawrence Livermore National Security, LLCInventors: Sally DeNardo, Gerald DeNardo, Rodney Balhorn
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Patent number: 7335744Abstract: This invention provides novel prostate cancer specific internalizing human antibodies. The antibodies are useful by themselves to prevent growth and/or proliferation of prostate cancer cells. The antibodies can also be formulated as chimeric molecules to direct an effector (e.g. a cytotoxin, an imaging reagent, a drug, etc.) to a prostate tumor site.Type: GrantFiled: December 21, 2004Date of Patent: February 26, 2008Assignee: The Regents of the California UniversityInventors: Bin Liu, James D. Marks
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Patent number: 7332585Abstract: Bispecific single chain antibody molecules are disclosed which may be used to advantage to treat various forms of cancer associated with the overexpression of members of the EGFR protein family.Type: GrantFiled: June 15, 2005Date of Patent: February 19, 2008Assignees: The Regents of the California University, Fox Chase Cancer CenterInventors: Gregory P. Adams, Eva M. Horak, Louis M. Weiner, James D. Marks
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Patent number: 6573997Abstract: A new interferometry configuration combines the strengths of two existing interferometry methods, improving the quality and extending the dynamic range of both. On the same patterned mask, placed near the image-plane of an optical system under test, patterns for phase-shifting point diffraction interferometry and lateral shearing interferometry coexist. The former giving verifiable high accuracy for the measurement of nearly diffraction-limited optical systems. The latter enabling the measurement of optical systems with more than one wave of aberration in the system wavefront.Type: GrantFiled: July 17, 2000Date of Patent: June 3, 2003Assignee: The Regents of CaliforniaInventors: Kenneth Alan Goldberg, Patrick P. Naulleau
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Publication number: 20020127239Abstract: An antigenic preparation is provided containing an outer membrane protein associated with pathogenic strains of Leptospira. The protein has been designated ALipL32″ for Alipoprotein from Leptospira≅ and because the isolated polypeptide migrates to a position corresponding to a molecular weight of 32 kD in a denaturing polyacrylamide gel. The invention provides polynucleotides encoding LipL32 and antibodies that bind the protein which are useful in the diagnosis of leptospirosis. In addition, LipL32 can be used immunologically as a vaccine for spirochete-associated pathologies.Type: ApplicationFiled: August 8, 2001Publication date: September 12, 2002Applicant: The Regents of California UniversityInventor: David A. Haake
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Patent number: 5658545Abstract: The present invention relates to a process of using metal particles to reduce NO to NH.sub.3. More specifically, the invention concerns an improved process to regenerate iron (II) (CHELATE) by reduction of iron (II) (CHELATE) (NO) complex, which process comprises: a) contacting an aqueous solution containing iron (II) (CHELATE) (NO) with metal particles at between about 20.degree. and 90.degree. C. to reduce NO present, produce ammonia or an ammonium ion, and produce free iron (II) (CHELATE) at a pH of between about 3 and 8. The process is useful to remove NO from flue gas and reduce pollution.Type: GrantFiled: March 29, 1995Date of Patent: August 19, 1997Assignee: The Regents of CaliforniaInventors: Shih-Ger Chang, David Littlejohn, Yao Shi