Abstract: Synthetic A? peptides, oligomers, their methods of synthesis, and their applications are provided. The A? peptides can form stable, soluble oligomers important for the advancement of knowledge, detection, and treatment of Alzheimer's disease. Antibodies specific to oligomeric A? and their methods of synthesis are also described.
Type:
Grant
Filed:
October 26, 2017
Date of Patent:
May 26, 2020
Assignee:
The Regents of the University of Caiifomia
Inventors:
James S. Nowick, Adam G. Kreutzer, Ryan K. Spencer, Patrick J. Salveson