Abstract: The application relates to methods of treating chronic viral infection by modulating Tim-3 activity. In addition, the present application relates to methods of diagnosing or monitoring immune system activity or function, chronic viral infection and inflammatory disease using Tim-3 expression.
Type:
Grant
Filed:
July 13, 2016
Date of Patent:
March 1, 2022
Assignees:
Altor BioScience, LLC., The Regents of the University of Califoria
Inventors:
Richard B. Jones, Mario Ostrowski, Douglas F. Nixon, Lishomwa C. Ndhlovu, James Rini