Patents Assigned to The Regents of the University of California Office of Technology Management
  • Activity-dependent cysteine protease profiling reagent
    Publication number: 20020150961
    Abstract: Probes are provided having specificity for papain cysteine hydrolases comprising an electrophile, exemplified by an epoxide, a hydrophobic group for fitting into the hydrolase pocket and a moiety that provides for detection and/or isolation. A variety of compound having hydrophobic side chains from an oligopeptide are exemplified using fluorescers, ligand members of specific binding pairs or radioactive labels for detection and/or isolation.
    Type: Application
    Filed: November 8, 2001
    Publication date: October 17, 2002
    Applicant: The Regents of the University of California Office of Technology Management
    Inventors: Matthew Bogyo, Doron Greenbaum