Patents Assigned to The Regenys of the University of Michigan
  • Biosynthetic pathway for heterologous expression of a nonribosomal peptide synthetase drug and analogs
    Patent number: 8815562
    Abstract: The present invention is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention also discloses polynucleotide sequences useful for heterologous expression in a convenient microbial host for the synthesis of the NRPS derived drug.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: August 26, 2014
    Assignees: The Regenys of the University of Michigan, Allegheny-Singer Research Institute, Colorado State University Research Foundation
    Inventors: David H. Sherman, Garth D. Ehrlich, Benjamin Janto, Robert M. Williams, Christopher M. Rath