Abstract: Compositions and methods for preventing and treating wasting disorders, such as cachexia and anorexia, are provided. In one aspect, the present invention provides a method for preventing and treating a wasting disorder in a mammal. In one embodiment, the method of the invention comprises administering to such mammal a macrolide and a ?2-adrenergic agonist in combination such that the macrolide and said ?2-agonist are administered in amounts effective to prevent or at least alleviate said wasting disorder.
Type:
Grant
Filed:
December 20, 2006
Date of Patent:
December 20, 2011
Assignee:
The Releef Initiative
Inventors:
Richard Kenley, Jonas Ekblom, Mikhail Denissenko