Patents Assigned to The Resarch Foundation for Microbial Diseases of Osaka Universtiy
  • Promoter for introducing a gene into a lymphocyte or blood cell and application thereof
    Patent number: 8013140
    Abstract: It is intended to provide a promoter for inducing expression selectively and strongly in an immunocompetent cell and/or a blood cell such as a lymphocyte. In the invention, the object was achieved by finding that HHV6 MIE promoter, HHV7 MIE promoter and HHV7 U95 promoter unexpectedly induce a specific expression in an immunocompetent cell and/or a blood cell such as a T lymphocyte. By utilizing the promoters, a selective delivery of a DNA vaccine or the like can be realized.
    Type: Grant
    Filed: August 21, 2008
    Date of Patent: September 6, 2011
    Assignee: The Resarch Foundation for Microbial Diseases of Osaka Universtiy
    Inventors: Masaya Takemoto, Yasuko Mori, Koichi Yamanishi, Isao Fuke, Yasuyuki Gomi, Michiaki Takahashi