Abstract: This invention relates to substantially purified gelonin, toxic fragments thereof, the DNA sequences encoding gelonin and use of the DNA for producing, by recombinant technology, gelonin, toxic fragments thereof and fusion proteins. More specifically, the invention relates to the primary amino acid sequence of gelonin, and of the DNA encoding said gelonin and the production of synthetic gelonin and toxic fragments thereof.
Type:
Grant
Filed:
June 6, 1994
Date of Patent:
May 20, 1997
Assignee:
The Research Development Foundation
Inventors:
Michael Rosenblum, William J. Kohr, Bharat Aggarwal
Abstract: This invention relates to substantially purified gelonin, toxic fragments thereof, the DNA sequences encoding gelonin and use of the DNA for producing, by recombinant technology, gelonin, toxic fragments thereof and fusion proteins. More specifically, the invention relates to the primary amino acid sequence of gelonin, and of the DNA encoding said gelonin and the production of synthetic gelonin and toxic fragments thereof.
Type:
Grant
Filed:
May 20, 1999
Date of Patent:
December 4, 2001
Assignee:
The Research Development Foundation
Inventors:
Michael Rosenblum, William J. Kohr, Bharat Aggarwal