Patents Assigned to The Research Foundation of the City University of New York
  • Methods and systems for treatment of spinal disorders using trans-spinal direct current stimulation
    Patent number: 10195424
    Abstract: Methods, systems and devices are disclosed for treating a spinal disorder by applying a source of direct current to a spinal cord in animals, including humans. Trans-spinal direct current stimulation (tsDCS) uses direct current via cathodal and/or anodal stimulation to induce cell proliferation, cell differentiation, and/or cell migration at or near the area of the spinal cord being treated, and up-regulates or down-regulates protein expression by cells at or near the area of the spinal cord being treated.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: February 5, 2019
    Assignee: THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventor: Zaghloul Ahmed
  • Mixed material cathode for secondary alkaline batteries
    Patent number: 10199639
    Abstract: A secondary alkaline battery using manganese dioxide is described. The battery includes a mixed cathode material with birnessite-phase manganese dioxide or electrolytic manganese dioxide (EMD), a bismuth compound and a copper compound selected from the group consisting of elemental copper and a copper salt. In some embodiments, a conductive carbon and/or a binder may also be included.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: February 5, 2019
    Assignee: Research Foundation of the City University of New York
    Inventors: Gautam G. Yadav, Joshua Gallaway, Michael Nyce, Sanjoy Banerjee
  • Method for inducing spin polarization in an analyte using N spin defect centers
    Patent number: 10180479
    Abstract: A method of inducing spin polarization in an analyte is provided. The method exposes 14N spin defect centers embedded within 25 nm of a diamond surface to a magnetic field while an analyte is near the surface. The 14N spin defect centers are polarized by treatment with an electromagnetic wave protocol having a visible light pulse (p0); a microwave pulse (mw1), a radio frequency pulse (rf1), a microwave pulse (mw2) and a radio frequency pulse (rf2) resulting in polarization of the nuclear spins of the 14N spin defect centers. Polarized spins in the 14N spin defect centers induce spin polarization in the analyte.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: January 15, 2019
    Assignee: Research Foundation of the City University of New York
    Inventors: Carlos A. Meriles, Daniela Pagliero, Abdelghani Laraoui
  • Method for identifying shortcoming in a building automation system (BAS)
    Patent number: 10156835
    Abstract: A Building Automation System Assessment Tool (BASAT) is provided. The BASAT receives input from a user that identifies the points associated with building systems controlled by Building Automation System (BAS) at a facility being surveyed. Based on the identified points, output reports are provided that identify shortcomings in the current BAS.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: December 18, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: Michael Bobker, Honey Berk, Marco Ascazubi
  • Solar powered water purification device with cylindrical structure
    Patent number: 10150049
    Abstract: A device for purifying water by solar power is described. The device has bottom and top sections, each being half-cylinders contacting one another along a flat edge to provide an elongated cylinder. The bottom section has an evacuated area with an optically transparent bottom surface that light can pass through to heat a liquid tray in the top section. A side-gutter directs water that condenses on an interior surface of the top section to an output port for collection.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: December 11, 2018
    Assignees: Research Foundation of the City University of New York, Sun Fresh Water, LLC
    Inventors: Joseph James D'Alba, George Victor St. Pierre, Ali M. Sadegh, Jorge E. Gonzalez
  • Solar powered water purification device with cylindrical structure
    Patent number: 10150050
    Abstract: A device for purifying water by solar power is described. The device has bottom and top sections, each being half-cylinders contacting one another along a flat edge to provide an elongated cylinder. The bottom section has an evacuated area with an optically transparent bottom surface that light can pass through to heat a liquid tray in the top section. A side-gutter directs water that condenses on an interior surface of the top section to an output port for collection.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: December 11, 2018
    Assignees: Research Foundation of the City University of New York, Sun Fresh Water, LLC
    Inventors: Ali M. Sadegh, Jorge E. Gonzalez-Cruz, Joseph James D'Alba, George Victor St. Pierre
  • Electrode assemblies for delivering therapeutic electrostimulation
    Patent number: 10143832
    Abstract: An apparatus for delivering therapeutic electrostimulation across a tissue surface includes a current source, a low current component adapted to contact the tissue surface, a first electrode assembly electrically connected to the current source and supported by the low current component, a second electrode assembly electrically connected to the current source and supported by the low current component and a conductive fluid supported by the low current component for facilitating a flow of electric current across the tissue surface. At least one of the first and second electrodes assemblies includes at least one of a magnetic electrode, a high current component and a non-current component.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: December 4, 2018
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Marom Bikson, Abhishek Datta, Niranjan Khadka
  • Layered microfluidic living cell array
    Patent number: 10144945
    Abstract: A layered, microfluidic living cell array is disclosed. The cell array comprises a first layer comprising at least one cell culture channel; a second layer comprising at least one microfluidic channel; and a third layer, disposed between the first layer and the second layer. The third layer comprises a filter membrane with a plurality of pores, each pore fluidly connecting the microfluidic channel to the cell culture channel.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: December 4, 2018
    Assignees: Research Foundation of the City University of New York, Memorial Sloan Kettering Cancer Center
    Inventors: Sihong Wang, Zeynep Dereli-Korkut, Xuejun Jiang
  • miRNAs useful for identifying targets associated with cancer
    Patent number: 10138481
    Abstract: Several miRNAs are described that are useful in diagnosing and treating prostate cancer, or pancreatic cancer. The miRNAs bind with targets that are associated with prostate cancer or pancreatic cancer. This permits the identification of those targets as well as a treatment methodology for prostate cancer.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: November 27, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: Olorunseun O. Ogunwobi, Dibash K. Das
  • Scavenger receptor uptake for fabry disease enzyme replacement therapy
    Patent number: 10138474
    Abstract: The present invention relates to a composition comprising a lysosomal enzyme conjugated to a negatively charged scavenger receptor ligand. In some embodiments, the lysosomal enzyme is conjugated to the scavenger receptor ligand by way of a linker. The present invention also relates to a composition comprising lysosomal enzyme encapsulated by a liposome, said liposome externally comprising a negatively charged scavenger receptor ligand. The invention further encompasses a method of treating a lysosomal storage disease with the compositions listed above. The invention further encompasses a method of treating a lysosomal storage disease with an acylated, acetylated, or aconitylated lysosomal enzyme.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: November 27, 2018
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: David H. Calhoun, Lane Gilchrist
  • Self-suspending modified proppant system for carbon dioxide based fracturing fluids
    Patent number: 10131834
    Abstract: Self-suspending proppants including proppant particles coated with a CO2-philic coating are provided. The CO2-philic coating may be lightly crosslinked and may have a physical structure that constrains CO2 molecules. Methods of making self-suspending proppants may include coating a proppant particle with a polymerizable precursor material of a CO2-philic material and polymerizing the polymerizable precursor material to form a self-suspending proppant are also provided. Additionally, hydraulic fracturing fluids that may include a CO2-based fluid and the self-suspending proppants and methods of treating subterranean formations by contacting a subterranean formation with hydraulic fracturing fluid and propagating at least one subterranean fracture are provided.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: November 20, 2018
    Assignees: Aramco Services Company, Research Foundation of The City University of New York
    Inventors: Feng Liang, Ghaithan A. Al-Muntasheri, Leiming Li, B. Raghava Reddy, George John, Vidyasagar Adiyala
  • Self-suspending proppants for use in carbon dioxide-based fracturing fluids and methods of making and use thereof
    Patent number: 10131832
    Abstract: Self-suspending proppants including proppant particles coated with a CO2-philic coating are provided. The CO2-philic coating may be lightly crosslinked and may have a physical structure that constrains CO2 molecules. Methods of making self-suspending proppants may include coating a proppant particle with a polymerizable precursor material of a CO2-philic material and polymerizing the polymerizable precursor material to form a self-suspending proppant are also provided. Additionally, hydraulic fracturing fluids that may include a CO2-based fluid and the self-suspending proppants and methods of treating subterranean formations by contacting a subterranean formation with hydraulic fracturing fluid and propagating at least one subterranean fracture are provided.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: November 20, 2018
    Assignees: Aramco Services Company, Research Foundation of The City University of New York
    Inventors: Feng Liang, Ghaithan A. Al-Muntasheri, Leiming Li, B. Raghava Reddy, George John, Vidyasagar Adiyala
  • Multi-metal oxide ceramic nanomaterial
    Patent number: 10118862
    Abstract: A convenient and versatile method for preparing complex metal oxides is disclosed. The method uses a low temperature, environmentally friendly gel-collection method to form a single phase nanomaterial. In one embodiment, the nanomaterial consists of BaAMnBTiCOD in a controlled stoichiometry.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: November 6, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: Stephen O'Brien, Shuangyi Liu, Limin Huang
  • Power centroid radar
    Patent number: 10101445
    Abstract: A system for signal processing is provided that obviates the use of prior-knowledge, such as synthetic aperture radar (SAR) imagery, in time compressed signal processing (i.e. it can be knowledge unaided). The knowledge-unaided power centroid (PCKU) is found by evaluating a covariance matrix RSCM for its moments mi. Because RSCM uses a sample signal, rather than SAR data, the power centroid PCKU may be found without needing SAR data.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: October 16, 2018
    Assignee: Research Foundation of the City University of New York
    Inventor: Erlan Feria
  • Mobility device for visually impaired toddler
    Patent number: 10092476
    Abstract: A device for providing hands-optional mobility to a visually impaired toddler is disclosed. The device has a frame with vertical rods that connect to a toddler's body with a fastener. Curved surfaces at the distal ends of the rods slide along the floor and transmit tactile sensations to the toddler. Advantageously, the vertical rods are sufficiently flexible that the toddler cannot utilize the rods as walking aids.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: October 9, 2018
    Assignee: Research Foundation of the City University of New York
    Inventor: Grace Ambrose-Zaken
  • Methods for thickening hydrophobic liquids with amphiphilic esters
    Patent number: 10081748
    Abstract: The present invention relates to a method for thickening a hydrophobic liquid. When a hydrophobic liquid is thickened in accordance with the invention, the liquid becomes significantly denser. Preferably, the hydrophobic liquid becomes a gel.
    Type: Grant
    Filed: July 29, 2010
    Date of Patent: September 25, 2018
    Assignee: The Research Foundation of The City University of New York
    Inventors: George John, Swapnil R. Jadhav, Praveen Kumar Vemula
  • Method of priming plants against abiotic stress factors
    Patent number: 10071981
    Abstract: A method of reducing cellular damage to a plant by treating the plant with a compound containing an NO-releasing moiety and an H2S-releasing moiety covalently bonded to an aspirin derived core or a NOSH compound is claimed. The compounds may also be used in a method of priming a plant against abiotic stress factors and a method of promoting plant growth.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: September 11, 2018
    Assignees: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK, CYPRUS UNIVERSITY OF TECHNOLOGY
    Inventors: Khosrow Kashfi, Vasileios Fotopoulos
  • Clerodendrum viscosum and methods of use
    Patent number: 10059924
    Abstract: The present invention provides for a composition and formulations comprising an extract from Clerodendrum viscosum, and a method of obtaining the extract. The present invention also provides for a method of treating any disease where uncontrolled cellular proliferation occurs, such as cancers. In particular, the present invention provides a method for treating cervical cancer. The present invention also provides methods to inhibit proliferation and induce apoptosis of cancer cells.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: August 28, 2018
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Swami Nirmalananda Giri, Krishnaswami Raja, Jimmie Fata, Chong Sun, Rema Balambika, David Bolton
  • TCR(alpha)-LCR-derived gene regulatory cassettes
    Patent number: 10053708
    Abstract: A method of delivering a transgene to a cell is provided. The method uses a vector that contains a T-cell receptor alpha locus control region (TCR?LCR) derived gene regulatory cassette having fewer than 5.0-kb. The method delivers the transgene with spatiotemporally specific gene expression and silencing-prevention controls to a cell such that a predetermined subset of progeny cell-types express a gene product from the transgene. Other progeny of the cell diminish, or silence, the expression of the gene product.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: August 21, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: Benjamin D. Ortiz, Armin Lahiji
  • SELF-SUSPENDING PROPPANTS FOR USE IN CARBON DIOXIDE-BASED FRACTURING FLUIDS AND METHODS OF MAKING AND USE THEREOF
    Publication number: 20180230365
    Abstract: Self-suspending proppants including proppant particles coated with a CO2-philic coating are provided. The CO2-philic coating may be lightly crosslinked and may have a physical structure that constrains CO2 molecules. Methods of making self-suspending proppants may include coating a proppant particle with a polymerizable precursor material of a CO2-philic material and polymerizing the polymerizable precursor material to form a self-suspending proppant are also provided. Additionally, hydraulic fracturing fluids that may include a CO2-based fluid and the self-suspending proppants and methods of treating subterranean formations by contacting a subterranean formation with hydraulic fracturing fluid and propagating at least one subterranean fracture are provided.
    Type: Application
    Filed: September 12, 2017
    Publication date: August 16, 2018
    Applicants: Aramco Services Company, Research Foundation of The City University of New York
    Inventors: Feng Liang, Ghaithan A. Al-Muntasheri, Leiming Li, B. Raghava Reddy, George John, Vidyasagar Adiyala