Patents Assigned to The Research Foundation
  • Patent number: 11452291
    Abstract: One aspect of the present invention is directed to a composition. The composition includes a dispersion inducer comprising: H3C—(CH2)n—CHmCHmR, where is a single or double carbon-carbon bond, m is 1 or 2, n is 2 to 15, and R is a carboxylic acid, a salt, an ester, or an amide, where the ester or amide is an isostere or biostere of the carboxylic acid. The composition additionally contains an additive component selected from one or more of the group consisting of biocides, surfactants, antibiotics, antiseptics, detergents, chelating agents, virulence factor inhibitors, gels, polymers, pastes, edible products, and chewable products. The composition is formulated so that when it is contacted with a biofilm produced by a microorganism, where the biofilm comprises a matrix and microorganism on a surface, the dispersion inducer selectively acts on the microorganism and has a suitable biological response without a required direct effect on the matrix to disperse the biofilm.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: September 27, 2022
    Assignee: The Research Foundation for The State University
    Inventor: David G. Davies
  • Patent number: 11453884
    Abstract: A method is provided for producing modified mutant yeast and the resulting yeast that can be used as a platform for terpene production. The method includes chemical mutagenesis to effect ergosterol dependent growth in yeast. Subsequently, these yeast are subjected to an erg9 knockout mutation to thereby produce ergosterol dependent growth/erg9 knockout mutation yeast cell lines. The resulting yeast are well suited for use in the production of terpenes.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: September 27, 2022
    Assignee: UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
    Inventors: Joe Chappell, Xun Zhuang, Shuiqin Wu
  • Patent number: 11453937
    Abstract: Magnet microstructure manipulation in the solid state by controlled application of a sufficient stress in a direction during high temperature annealing in a single-phase region of heat-treatable magnet alloys, e.g., alnico-type magnets is followed by magnetic annealing and draw annealing to improve coercivity and saturation magnetization properties. The solid-state process can be termed highly controlled abnormal grain growth (hereafter AGG) and will make aligned sintered anisotropic magnets that meet or exceed the magnetic properties of cast versions of the same alloy types.
    Type: Grant
    Filed: October 5, 2020
    Date of Patent: September 27, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Iver E. Anderson, Emma Marie Hamilton White, Matthew J. Kramer, Aaron G. Kassen, Kevin W. Dennis
  • Patent number: 11452448
    Abstract: A system for determination of intraocular pressure includes: an intraocular pressure sensor; a light source illuminating the sensor with one or more wavelengths of light; and a detector that measures emitted light from the sensor. The sensor includes a substrate member, a spacer member, and a flexible membrane, which define a sealed cavity. The flexible membrane moves in response to intraocular pressure changes. A device for measuring intraocular pressure includes: the sensor; an anchoring member attached to the sensor for immobilizing the sensor in an eye; and a protective member attached to the anchoring member and covering the sensor to prevent contact between the flexible membrane and the eye. A method for determination of intraocular pressure includes: placing the sensor in an eye; illuminating, with a light source, the sensor with one or more wavelengths of light; and detecting, with a detector, a resultant light that contains information about intraocular pressure.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: September 27, 2022
    Assignees: UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, IOPTIC, INC.
    Inventors: Jeffrey Todd Hastings, E. Britt Brockman, Ingrid L. St. Omer, John C. Wright
  • Publication number: 20220299770
    Abstract: A display device and an electronic apparatus are disclosed. The display device comprises: an image-display component, which generates an image light output, wherein at least one pixel light of the image light output has light polarization components of at least two polarization states or has a polarization light component of a polarization state and a non-polarization light component; and a polarization dependent image offset component, which receives the image light output coming from the image display component and deflects the polarization light components based on the polarization states to separate each of the at least one pixel light into at least two pixel lights, or deflects the polarization light component from the non-polarization light component to separate each of the at least one pixel light into at least two pixel lights.
    Type: Application
    Filed: February 21, 2020
    Publication date: September 22, 2022
    Applicants: University of Central Florida Research Foundation, Inc., Goertek Inc.
    Inventors: Tao Zhan, Jianghao Xiong, Guanjun Tan, Yun-Han Lee, Shin-Tson Wu, Sheng Liu, Jilin Yang
  • Publication number: 20220299766
    Abstract: A head-mounted display apparatus and an optical display system are disclosed. The head-mounted display apparatus comprises: a display assembly, which outputs light of an image; a lens assembly, placed in front of the display assembly to enlarge the image and produce the first aberration of a first direction; and a planar optical assembly, placed between the display assembly and the lens assembly, wherein the planar optical assembly produces the second aberration of a second direction opposite to the first direction to correct the first aberration.
    Type: Application
    Filed: August 5, 2020
    Publication date: September 22, 2022
    Applicants: University of Central Florida Research Foundation, Goertek Inc.
    Inventors: Tao Zhan, Junyu Zou, Shin-Tson Wu, Sheng Liu, Jilin Yang
  • Publication number: 20220303159
    Abstract: A method for designing a channel estimation and data detection networks is provided herein. The problem of channel estimation for linear systems has effectively been solved—not the case for non-linear systems. A deep learning framework for channel estimation, data detection, and pilot signal design is described to address the nonlinearity in such systems.
    Type: Application
    Filed: March 18, 2022
    Publication date: September 22, 2022
    Applicant: San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation
    Inventors: Duy H.N. Nguyen, Van Ly Nguyen
  • Publication number: 20220302324
    Abstract: A photomultiplier containing a solid-state photoconductive film composed of amorphous selenium (a-Se) is provided. In the a-Se containing photomultiplier, a hole-blocking layer is provided that maximizes gain and maintains low dark conductivity. Also, the hole-blocking layer achieves reliable and repeatable impact ionization without irreversible breakdown. The hole-blocking layer is a non-insulating metal oxide having a dielectric constant (k) of greater than 10.
    Type: Application
    Filed: September 11, 2020
    Publication date: September 22, 2022
    Applicants: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, NEW YORK UNIVERSITY
    Inventors: Amirhossein GOLDAN, Wei ZHAO, Ayaskanta SAHU
  • Publication number: 20220298103
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: April 20, 2022
    Publication date: September 22, 2022
    Applicant: The Research Foundation for The State University of New York
    Inventors: Maurizio Del Poeta, Visesato Mor
  • Publication number: 20220298324
    Abstract: A transmission line is disclosed which includes a first conductor, a second conductor, a composite disposed between the first conductor and the second conductor, the composite includes non-linear inclusions comprising one or more of non-linear dielectric and non-linear magnetic inclusions mixed in a matrix material, wherein the non-linear dielectric inclusions are selected from the group consisting of barium strontium titanate (BST), barium titanate, strontium titanate, barium zirconate titanate, lead zirconate titanate, lead titanate, lithium niobate, potassium niobate, lead scandium tantalate, strontium barium niobate, and combinations thereof, and the non-linear magnetic inclusions are selected from the group consisting of nickel zinc ferrite (NZF), manganese zinc ferrite, cobalt ferrite, manganese ferrite, zinc ferrite, nickel ferrite, and combinations thereof, wherein the non-linear inclusions by volume are about 25% NZF, about 10% BST/15% NZF, and about 15% BST/10% NZF, and wherein the first conductor,
    Type: Application
    Filed: March 18, 2022
    Publication date: September 22, 2022
    Applicant: Purdue Research Foundation
    Inventors: Andrew Fairbanks, Allen L Garner
  • Publication number: 20220301805
    Abstract: A field emitter array (FEA) vacuum transistor is disclosed which includes a substrate and a plurality of nanorods formed of a first polarity dopant on the substrate, wherein the dopant density is between about 1013 cm?3 to about 1015 cm?3.
    Type: Application
    Filed: March 22, 2022
    Publication date: September 22, 2022
    Applicant: Purdue Research Foundation
    Inventors: Saeed Mohammadi, Shabnam Ghotbi
  • Publication number: 20220296720
    Abstract: Composite composition comprising chitosan, tannin, and an active agent and methods of making and using same.
    Type: Application
    Filed: November 9, 2021
    Publication date: September 22, 2022
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Jess Reed, Christian Krueger
  • Patent number: 11446264
    Abstract: Provided is a method of inhibiting protein kinase C zeta/protein kinase M zeta, including contacting a sample containing an isoform of protein kinase C zeta with a compound of formula: referred to as 1-naphthol-3,6,8-trisulphonic acid, or a pharmaceutically acceptable salt thereof. In some embodiments, contacting the sample with the compound does not inhibit protein kinase C iota/lambda. In a specific example, the sample includes neural tissue, the isoform of protein kinase C zeta is protein kinase M zeta, and inhibiting includes reducing kinase activity and further includes diminishing long-term potentiation. In some embodiment, the method includes inhibiting glucose transport. Also provided is a method of affecting memory, including administering the compounds to a mammalian organism.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: September 20, 2022
    Assignees: THE RESEARCH FOUNDATION FOR THE STATE UNIVERISTY OF NEW YORK, UNIVERSITY OF SOUTH FLORIDA
    Inventors: Todd Sacktor, Mildred Acevedo-Duncan
  • Patent number: 11447754
    Abstract: Enzymes for depolymerizing lignin. The enzymes include dehydrogenases, ?-etherases, and glutathione lyases. The dehydrogenases can comprise one or more or LigD, LigO, LigN, and LigL. The ?-etherases can comprise one or more of LigE, LigF, LigP, and BaeA. The glutathione lyases can comprise any one or more of LigG and a number of non-stereospecific, optionally recombinant glutathione lyases derived from Sphingobium sp. SYK-6, Novosphingobium aromaticivorans, Escherichia coli, Streptococcus sanguinis, Phanerochaete chrysosporium, and other microorganisms. The enzymes can be combined in compositions and/or used in methods of processing lignin or other aromatic compounds in vitro.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: September 20, 2022
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Timothy James Donohue, Daniel Leo Gall, Wayne S. Kontur, Hoon Kim, John Ralph, Daniel R. Noguera, Brian Fox, Craig Bingman
  • Patent number: 11447405
    Abstract: A method and apparatus are provided for removing EPA regulated chemical species from industrial wastewater using green rust. The apparatus includes a green rust generator having an iron anode and a carbon cathode.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: September 20, 2022
    Assignee: University of Kentucky Research Foundation
    Inventors: Xin Gao, Kunlei Liu, James R. Landon, Jesse Thompson, Ayokunle O. Omosebi, Keemia Abad, Zilong Ma
  • Patent number: 11450385
    Abstract: One embodiment provides a resistive random-access memory (RRAM) based convolutional block including a complementary pair of RRAMs having a first RRAM and a second RRAM, a programming circuit coupled to the complementary pair of RRAMs, and a XNOR sense amplifier circuit coupled to the complementary pair of RRAMs. The programming circuit is configured to receive a kernel bit from a kernel matrix, program the first RRAM to at least one selected from a group consisting of a low resistive state (LRS) and a high resistive state (HRS) based on the kernel bit, and program the second RRAM to other of the LRS and the HRS. The XNOR sense amplifier circuit is configured to receive an input bit from an input matrix, perform a XNOR operation between the input bit and the kernel bit read from the complementary pair of RRAMs, and output a XNOR output based on the XNOR operation.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: September 20, 2022
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Pierre-Emmanuel Gaillardon, Edouard Giacomin, Joao Vieira
  • Patent number: 11446392
    Abstract: The present disclosure relates to unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. The disclosed compositions are useful for treating a subject with a disease or condition, such as a cardiovascular disease. In a further aspect, the cardiovascular disease can be a vascular stenosis or restenosis. Also described herein are methods of making and using the unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: September 20, 2022
    Assignees: Ohio State Innovation Foundation, Wisconsin Alumni Research Foundation
    Inventors: K. Craig Kent, Shaoqin Gong, Lianwang Guo, Bowen Wang, Guojun Chen, Go Urabe
  • Patent number: 11447768
    Abstract: The subject invention pertains to a Molecular Cell Diary System (MCDS), which allows identification of the history of somatic alterations in the cell. MCDS comprises one or more combinations of a DNA cutter and a DNA writer expressed under the control of a promoter controlled a cellular event of interest. The DNA cutter and the DNA writer are in a combination are co-expressed when an even of interest occurs. The DNA cutter creates double strand breaks (DSB) in a target DNA in a sequence specific manner and the DNA writer incorporates DNA sequences in the DSB. The endogenous DNA repair machinery synthesizes repairs the DSB. As such, the combination of the DNA cutter and the DNA writer modifies the target DNA and leaves “marks” of the occurrence of the cellular event of interest. These marks are sequenced and the cellular event history of the cell is deciphered.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: September 20, 2022
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: David Tran, Son Le
  • Patent number: 11450220
    Abstract: An apparatus is disclosed for conditioning and adapting an individual to real-world environments through computer simulations. The subject is fully or partially immersed in a computer-simulated environment for a time-limited session. Real-time monitoring of the human subject is performed for a change in a sensor-derived, quantified sensory load level. Responsive to an increase in sensory load level, the computer-simulated environment modulates the sensory complexity of one or more features of the simulation wherein the human subject adapts to increasingly complex environments.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: September 20, 2022
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Lisa A. Dieker, Michael Hynes, Charles Hughes, Eleazar Vasquez, Kathleen Ingraham, Claire Donehower, Taylor Bousfield
  • Patent number: 11449987
    Abstract: A method of detecting the presence of a prostate cancer in a human subject comprising the steps of (a) obtaining a histologically normal prostate tissue sample from the patient and (b) quantifying the epithelial thickness or gland lumen roundness of the tissue, wherein an increase in epithelial thickness or a decrease in gland lumen roundness indicates the presence of prostate cancer or a prostate cancer field defect.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: September 20, 2022
    Assignees: Wisconsin Alumni Research Foundation, The Medical College of Wisconsin, Inc.
    Inventors: David Frazier Jarrard, Bing Yang, Peter LaViolette