Patents Assigned to The Rockefeller Universtiy
  • APOE GENOTYPING IN CANCER PROGNOSTICS AND TREATMENT
    Publication number: 20220127680
    Abstract: This disclosure presents methods and reagents for cancer prognosis and treatment based on APOE genotyping. Specifically, the presence of the APOE2 genotype is indicative of a poor prognosis for the subject, whereas the presence of the APOE4 genotype is indicative of a good prognosis for the subject. The disclosed methods and reagents are useful for treating cancer and for making medical and clinical decisions on adjuvant therapy, tumor surveillance, and the likelihood of disease progression.
    Type: Application
    Filed: February 28, 2020
    Publication date: April 28, 2022
    Applicant: The Rockefeller Universtiy
    Inventors: Sohail Tavazoie, Benjamin N. Ostendorf, Masoud Tavazoie, Foster Gonsalves
  • BROADLY-NEUTRALIZING ANTI-HIV ANTIBODIES
    Publication number: 20190345233
    Abstract: The present invention relates to anti-HW antibodies. Also disclosed are related methods and compositions. HIV causes acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immuno suppression that results in life-threatening opportunistic infections and malignancies. Since its discovery in 1981, HIV type 1 (HIV-1) has led to the death of at least 25 million people worldwide.
    Type: Application
    Filed: July 10, 2019
    Publication date: November 14, 2019
    Applicants: The Rockefeller Universtiy, California Institute of Technology
    Inventors: Hugo Mouquet, Michel Nussenzweig, Pamela J. Bjorkman, Louise Scharf
  • Broadly-Neutralizing ANTI-HIV Antibodies
    Publication number: 20180282400
    Abstract: The present invention relates to anti-HIV antibodies. Also disclosed are related methods and compositions. HIV causes acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies. Since its discovery in 1981, HIV type 1 (HIV-1) has led to the death of at least 25 million people worldwide.
    Type: Application
    Filed: June 12, 2018
    Publication date: October 4, 2018
    Applicant: The Rockefeller Universtiy
    Inventors: Hugo Mouquet, Michel Nussenzweig, Pamela J. Bjorkman, Louise Scharf
  • Ply-GBS mutant lysins
    Patent number: 8105585
    Abstract: Methods, compositions and articles of manufacture useful for the treatment of various Group B streptococci (GBS) bacteria using various lysins, including certain PlyGBS mutant lysins, are provided.
    Type: Grant
    Filed: August 17, 2006
    Date of Patent: January 31, 2012
    Assignee: The Rockefeller Universtiy
    Inventors: Vincent A. Fischetti, Qi Cheng