Patents Assigned to The Royal Society
  • Live vaccines
    Patent number: 5851519
    Abstract: The present invention discloses a novel approach to attenuating bacteria and for their use as live vaccines. The vaccines can be used in human and animal medicine.In particular, there is disclosed a method of attenuating a bacteria by mutating a gene concerned with the regulation of one or more genes concerned with expression of outer membrane proteins, particularly porin proteins.
    Type: Grant
    Filed: April 10, 1995
    Date of Patent: December 22, 1998
    Assignees: Glaxo Wellcome Inc., The Royal Society, The Lister Institute of Preventive Medicine, The University Court of The University of Dundee
    Inventors: Gordan Dougan, Steven Neville Chatfield, Christopher Francis Higgins, Charles James Dorman
  • Vaccines comprising attenuated salmonella having mutations in the ompr genes
    Patent number: 5527529
    Abstract: The present invention discloses a novel approach to attenuating bacteria and for their use as live vaccines. The vaccines can be used in human and animal medicine.In particular, there is disclosed a method of attenuating a bacteria by mutating a gene concerned with the regulation of one or more genes concerned with expression of outer membrane proteins, particularly porin proteins.
    Type: Grant
    Filed: April 10, 1995
    Date of Patent: June 18, 1996
    Assignees: The Wellcome Foundation Limited, The Royal Society, The Lister Institute of Preventive Medicine, The University Court of The University of Dundee
    Inventors: Gordan Dougan, Steven N. Chatfield, Christopher F. Higgins, Charles J. Dorman