Abstract: The present invention relates to a mutated Francisella bacterium, wherein the ggt gene is silenced or deleted; pharmaceutical compositions comprising the same, in particular, vaccine compositions, and use of the bacterium and compositions for treatment and/or prophylaxis, and in particular, the treatment or prophylaxis of tularemia.
Type:
Application
Filed:
April 14, 2010
Publication date:
May 3, 2012
Applicant:
THE SECETART OF STATE FOR DEFENCE
Inventors:
Helen Le Butt, Phillip Matthew Ireland, Petra Claire Farquar Oyston